November 30, 2022

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Which liver disease patients are more likely to progress to cirrhosis?

Which liver disease patients are more likely to progress to cirrhosis?

 

Which liver disease patients are more likely to progress to cirrhosis? In terms of the causes of liver cirrhosis, hepatitis B and C virus infections are more familiar, in addition to fatty liver, drugs, alcohol consumption, autoimmune disorders, genetic metabolic diseases, and parasites. Sexual diseases, heart failure, nutritional disorders, etc.

Which liver disease patients are more likely to progress to cirrhosis?

 


In terms of the causes of liver cirrhosis, hepatitis B and C virus infections are more familiar, in addition to fatty liver, drugs, alcohol consumption, autoimmune disorders, genetic metabolic diseases, and parasites. Sexual diseases, heart failure, nutritional disorders, etc.

 

Then these factors will cause chronic inflammation of the liver. If liver function is repeatedly abnormal and inflammation occurs repeatedly in the liver, the body must repair these inflammations, which will lead to the proliferation of fibrotic tissue in the liver tissue.

This is just like scars on our hands if we have wounds. As long as there is inflammation, there will be fibrosis. The heavier the inflammation, the heavier the fibrosis, the longer the inflammation lasts, and the more scar tissue is produced.

At this time, if you do a B-ultrasound, you will find that the liver light spots in the liver tissue become dense with the progress of the disease. The light spots increase, the light spots become thicker, and even nodules appear. The morphology of the liver will also show uneven surface or even jagged changes. These changes are caused by the increase in scar tissue in the liver.

 

Taking hepatitis B patients as an example, the patient’s disease progression is mainly due to the following reasons:

1) Age over 40: The older the age, the greater the possibility of hepatitis B progression. It is generally believed that over 40 is more dangerous; age and etiology are factors that affect the progression of liver disease to cirrhosis;

2) Male patients. Men are more likely to develop than women;

3) A family history of liver cancer and liver cirrhosis. People with a family history of liver cancer are more likely to progress; many patients in Asia have a family history of liver cancer, so Asians are more likely to develop liver cancer and cirrhosis.

4) Bad lifestyle: smoking, alcoholism, staying up late, overwork, etc.

5) Environmental factors: In some places, the living environment is not good, food and water sources are easily polluted, which are also dangerous factors;

6) Viral factors. Including high viral load, hepatitis B virus genotype, co-infection with hepatitis B and C, virus mutation, etc. To prevent the progression of the disease, it is necessary to control the controllable factors. Early intervention can reduce the occurrence of liver cirrhosis and liver cancer.


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