October 20, 2021

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Why is the cheap and easy-to-use Penicillin used rarely now ? 

Why is the cheap and easy-to-use Penicillin used rarely now ? 


Why is the cheap and easy-to-use Penicillin used rarely now ? Penicillin, regarded as the greatest life-saving medicine during World War II, opened the era of antibiotics and saved countless lives. It can be said to be an epoch-making discovery at that time.

However, penicillin, which was once popular all over the world, is now hard to see penicillin in clinics, community hospitals, or outpatient infusion halls of municipal or provincial tertiary hospitals. Why?

Why is the cheap and easy-to-use Penicillin used rarely now ? 


Why is penicillin rarely seen now?

(1) Price factor

Compared with cephalosporin, penicillin is cheaper. Therefore, many patients or doctors believe that the price is the guarantee of the quality of the medicine, but also the guarantee of the treatment effect! Therefore, it is clinically biased to choose cephalosporin for prevention or treatment.

(2) Allergic factors

We all know that penicillin drugs have a high allergy rate and may cause anaphylactic shock and other fatal diseases. Therefore, whether it is oral or injection preparations, skin tests are required before use. However, putting aside the skin test is the painful memory of many of us. The probability of false negative and false positive results of the skin test is still relatively high, and the unscientific nature of the skin test itself, the successive listing of cephalosporin drugs and other factors have made penicillin popular. The degree plummeted.

(3) Resistance factors

As an antibacterial drug that opened the era of antibiotics, penicillin has been used for a long time and has a wide range of use. I still remember when I was a child, I still remember that when I had a headache or a cough when I was young, my parents would ask the barefoot doctor to give me sling for me because I didn’t dare to delay my studies, and I often recovered alive the next day after slinging. Therefore, in many cases, clinicians grab eyebrows and beards without careful identification. Although there is no indication for use, antibiotics will be given to patients. Long-term abuse and bacterial mutation have led to antibiotic resistance. In layman’s terms, it is not before. So good!



Finally, it needs to be pointed out that sometimes penicillin can still play an important role in the infection of some special microorganisms. In addition, the penicillin we just mentioned refers to natural penicillin in a narrow sense. However, the penicillin family is relatively large. The broad-spectrum penicillin and anti-Pseudomonas aeruginosa penicillin compound preparations derived later, such as amoxicillin clavulanate potassium, piperacillin tazobactam, etc., are clinically The application is still relatively extensive. Then, as patients and physicians, we should all grasp the principles, use antibacterial drugs rationally, and contribute our own strength to delaying antibiotic resistance!

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