- Will CAR-NK Cancer Therapy Surpass High-Cost CAR-T Immunotherapy?
- What is the role of Platelet Dynamics in Cancer Progression?
- Biomarkers can detect rapid aging of organs and disease risks
- Avoiding “Off-Target” Effects: Researchers Enhance the Safety of Future mRNA Therapies
- Japan: Sales Halted for ‘Cannabis Gummies’ as Health Issues Mount
- Evaluation of the carcinogenicity of organic fluorine compounds raised by WHO subsidiary
Diabetes must also monitor glycosylated hemoglobin
Diabetes must also monitor glycosylated hemoglobin. Don’t think that it’s OK to control your blood sugar on an empty stomach and after a meal! This indicator is the most critical.
For diabetes patients, in addition to monitoring fasting and postprandial blood sugar, they must also monitor glycosylated hemoglobin.
Fasting blood glucose of 9-10mmol/L is definitely not normal, so to judge whether it is serious, it is necessary to combine postprandial blood sugar, especially glycosylated hemoglobin, to comprehensively judge the blood sugar situation.
In order to judge the severity of a person with diabetes, in addition to the control of blood sugar, the age of onset, the age of onset, the comorbid diseases, whether the organs are damaged, etc., can be used to determine whether the diabetes is serious.
How much blood sugar should you consider diabetes?
1. Fasting blood sugar:
Normal fasting blood glucose reference value: glucose oxidase method: 3.9~6.1mmol/L, o-toluidine method: 3.9~6.4mmol/L; that is, the blood glucose of normal people should not exceed 6.4mol/L; if fasting blood glucose is ≥7.0 mmol/L, it is necessary to consider the diagnosis of diabetes. So when the blood sugar is 9-10mmol/L, it is diabetes.
Diabetics not only need to look at fasting blood glucose, but also refer to postprandial blood glucose.
2. Postprandial blood sugar
Oral glucose tolerance test: 30 minutes to 1 hour, the normal value is 7.8 to 9.0 mmol/L, not more than 7.8 mmol/L after 2 hours, and the fasting blood glucose level should be restored after 3 hours. When random blood glucose ≥ 11.1mmol/L, diabetes can be diagnosed.
Therefore, it is recommended that when the fasting blood glucose is 9-10, you must check a postprandial blood glucose, because for hypoglycemic treatment, you need to refer to the fasting and postprandial blood glucose.
So is it enough to have fasting blood glucose and postprandial blood glucose?
3. Of course not. As a diabetic, he should pay more attention to glycosylated hemoglobin:
The results of fasting and post-meal or random blood glucose are sometimes affected by factors such as the time of blood test, whether insulin is used or not. Sometimes there will be a certain deviation, so a more accurate indicator of the recent blood sugar situation is glycosylated hemoglobin. It can effectively reflect the blood sugar control of diabetic patients in the past 1 to 2 months.
Glycated hemoglobin is an important method for diagnosing and managing diabetes, and it is also the gold standard for measuring blood sugar control. The reference value of normal human glycosylated hemoglobin determination is: 4% to 6%.
The higher the glycosylated hemoglobin, the poorer the recent blood sugar control, and the more serious it is. However, to judge whether a diabetic patient is serious or not, the medical history must also be obtained. For example, the longer the time, the greater the relative risk; if it is not found in time, the longer the incubation time. , The greater the harm; the greater the harm if diabetes occurs without active and timely control.
The most important thing is to see if there is any organ damage caused by diabetes.
The reason why diabetes is so harmful is that long-term diabetes can lead to aggravation of systemic atherosclerosis, leading to cardiovascular and cerebrovascular diseases; not only that, diabetes can also cause organ damage such as kidney failure.
Complications caused by diabetes:
1. Acute coma:
If blood sugar control is extremely poor, then acute life-threatening complications may occur: diabetic ketoacidosis, lactic acidosis, and hyperosmolar hyperglycemia conditions will lead to confusion, coma, and even death. Rescue in time.
Many people have controlled their blood sugar and have not experienced serious diabetic coma. They think that their blood sugar is well controlled, and never monitor or rarely monitor, that is not undesirable.
This is because we try to strictly control diet + regular medication to keep blood sugar at or close to the ideal level.
If blood sugar control is not satisfactory, long-term high blood sugar may lead to:
2. Organ damage:
Coronary heart disease is the most important complication of diabetes, and it is life-threatening at any time when it develops into acute myocardial infarction. In patients with coronary heart disease with diabetes, coronary heart disease is often found late, because it affects the nervous system, feels slow, and has atypical symptoms of angina pectoris. As a result, multiple blood vessels are severely narrowed. Can not be treated with stents, many require bypass surgery.
Causes cerebral infarction, hemiplegia, aphasia, hemiplegia, and even fatal; diabetic nephropathy, renal failure; diabetic eye complications, blurred vision and blindness; diabetic foot, amputation; diabetic peripheral neuropathy, limb numbness, electric puncture and other sensations.
If these complications have already occurred, then they must be serious; for cases where there are no complications for the time being, we have to resort to glycosylated hemoglobin.
How well the glycosylated hemoglobin is controlled can also reflect the severity of diabetes:
According to the latest research, elevated glycosylated hemoglobin often leads to severe stenosis of the three major blood vessels of the heart and easily leads to heart failure; it is often fatal.
Compared with non-diabetic patients, the risk of diabetic patients with poorer heart function, tachycardia, and multivessel coronary artery disease increased by 12%, 40%, and 42%, respectively. For every 1% increase in glycosylated hemoglobin level, the risk of tachycardia and multivessel coronary artery disease increases by 11%. Even in patients with glycated hemoglobin level ≤6.5%, the risk of multivessel coronary artery disease is still 30% higher than that of non-diabetic patients. In patients with glycosylated hemoglobin levels >7%, the risk of multivessel coronary artery disease increased by 49%.
The stenosis of multiple blood vessels in the heart blood vessels is naturally more dangerous and more serious. To a certain extent, glycosylated hemoglobin can reflect the degree of stenosis of the vascular disease. That is to say, glycosylated hemoglobin can, to a certain extent, judge whether a diabetic patient is serious. Therefore, for friends with diabetes, in addition to monitoring fasting and postprandial blood sugar, they must also monitor glycosylated hemoglobin.
But no matter what, for every diabetic patient, on the basis of strict control of diet, appropriate exercise, and under the guidance of doctors’ regular medication, recommendations: fasting blood glucose 6-7mmol/L, postprandial blood glucose 5-10mmol/L, glycation Hemoglobin is 6.5-7%; this level is ideal, of course, even if it does not meet the standard, it should be as close as possible to this level.
(source:internet, reference only)