October 4, 2023

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What factors can cause fatty liver to develop into liver cancer?

What factors can cause fatty liver to develop into liver cancer?


What factors can cause fatty liver to develop into liver cancer? From fatty liver to liver cancer, there are only 5 steps!

Step1: simple fatty liver

The liver “gains fat”, and the fat squeezes the liver cells to one side. The liver is a silent organ. Early fatty liver is neither painful nor itchy. However, there is more fat in the liver cells, which will make the liver very sensitive, and the body is prone to fatigue, colds, fever, and diarrhea.


Step 2: Steatohepatitis

Simple fatty liver continues to increase, and the liver seems to be wearing a thick “cotton”, breathing is difficult, nutrition is difficult to deliver, liver cells will degenerate and necrosis, and the liver will start to become inflamed.


Step 3: Liver Fibrosis

If liver fibrosis inflammation continues, it will stimulate the proliferation of fibrous tissue in the liver.


Step 4: Liver Cirrhosis

Fibrous tissue increases and becomes harder, which leads to liver cirrhosis.


Step 5: Liver Cancer

After liver cirrhosis, if the patient is also accompanied by diabetes, obesity, hyperlipidemia, and endocrine disorders, the body’s internal environment and immune system function abnormally, resulting in a decline in the immune system’s ability to monitor tumor occurrence, unable to remove abnormal mutant cells, and then become cancerous.


Diseased caused by fatty liver:


1. Liver Cancer


2. Fatty liver will cause the function of various organs in the body to decline

The accumulation of fat in the liver reduces the ability of the liver to synthesize albumin, which is an important protein that maintains the function of tissues and organs. People with low albumin have poor appetite, fatigue and weakness, and are susceptible to various diseases.


3. Fatty liver can cause digestive system diseases

Fatty liver directly affects the digestive function of the liver, causing indigestion, loss of appetite, anorexia, and often feeling abdominal distension, nausea, and lipid metabolism disorders after eating. Long-term loss of appetite will cause a person to suffer from listlessness, neurasthenia, dry skin, and dull complexion, which will seriously affect work and study.


4. Fatty liver can cause atherosclerosis and cardiovascular and cerebrovascular diseases

Fatty liver patients are often accompanied by hyperlipidemia, high cholesterol, etc. The blood viscosity increases, the vascular cavity becomes smaller, the blood vessels lose their original elasticity, blood flow slows down, and thrombosis is easy to form, which eventually leads to thickening and hardening of the vascular wall, forming arteries Atherosclerosis. As a result, the heart cannot get a sufficient blood supply, which can cause cardiac ischemia, myocardial spasm, angina or myocardial infarction. Insufficient blood supply or rupture of blood vessels in the brain can cause cerebral infarction and cerebral hemorrhage.

Patients with type 2 diabetes and chronic kidney disease have an increased risk of cardiovascular disease. If fatty liver occurs on the basis of type 2 diabetes and chronic kidney disease, the risk of cardiovascular disease will further increase by 1.7 times and 2 times in the future.


5. Fatty liver affects vision

The liver opens up to the eyes, and the eyes can see things because of the dredging of liver qi and the nourishment of liver blood. The eyes are in close contact with the liver. Whether the liver function is normal, usually there is a reaction in the eyes. Patients with fatty liver often show transient blackening in front of their eyes, invisible to the surrounding objects, and recover after a while; the eyes are very fatigued when reading; the distant objects cannot be seen clearly; the eyes are dry; the vision is reduced.


6. Fatty liver affects sexual function

Fatty liver can cause obstacles to the inactivation mechanism of hormones in the body. The level of estrogen in the male body is relatively high, and there are obvious female sexual characteristics. The prominent manifestations are abnormal breast development, mammary gland hyperplasia, nipple melanosis, and testicles become smaller and softer. , Impotence, premature ejaculation, loss of libido, etc.


7. Often feel uncomfortable

In fact, in addition to inducing malignant liver diseases, such as liver fibrosis and cirrhosis, the hazards of fatty liver are mainly manifested in making people in a sub-healthy state all day long, often causing insomnia, fatigue, reluctance to eat, gastrointestinal dysfunction, and sexual function Discomfort such as diminished.

Authoritative data show that many sub-health symptoms of the human body are caused by fatty liver, such as upper abdominal discomfort, anorexia, bloating, nausea, vomiting, indigestion, diarrhea due to a slight improper diet, etc., and frequent nose bleeding, Bleeding gums, intermittent purple spots (gray-black spots) on the skin, and varying degrees of anemia, or frequent peripheral neuritis, angular cheilitis, skin ecchymosis, and hyperkeratosis.


8. Fatty liver can cause obstructive sleep apnea syndrome.

Fatty liver and obstructive sleep apnea syndrome often occur in severely obese people. Compared with people without obstructive sleep apnea syndrome, patients with obstructive sleep apnea syndrome have an increased risk of steatohepatitis, a 3.19-fold increase in the risk of hepatocyte steatosis, a 2.85-fold increase in the risk of lobular inflammation, and the risk of ballooning degeneration Increased by 2.29 times, the risk of liver fibrosis increased by 2.49 times.


9. Fatty liver leads to shortened lifespan

Fatty liver caused by different etiologies and the underlying diseases that accompany it will all have a slight or severe, near or far impact on the life of the patient. For example, patients with obesity and diabetes complicated with fatty liver, although there is no life worry, but the quality of life is greatly reduced. The survey shows that fatty liver disease can shorten the life span of patients under 50 by 4 years and shorten the life span of patients over 50 by 10 years. Long-lived people over 90 years old may suffer from cardiovascular and cerebrovascular diseases, lung diseases, and kidney diseases, but liver diseases are rare. It can be seen that the health of the liver has a direct and profound impact on human life.


10. Fatty liver and extrahepatic tumors

Studies have shown that the cancer incidence of fatty liver patients is 1.32 times higher than that of non-fatty liver patients, among which hepatocellular carcinoma is 16.73 times higher, cholangiocarcinoma is 1.95 times higher, male colorectal cancer is 2.01 times higher, and female breast cancer is 1.92 times higher. The risk of tumors in type 2 diabetes patients with fatty liver increased by 1.1 times. The more severe liver fibrosis, not only the higher the incidence of hepatocellular carcinoma, but also the higher the incidence of extrahepatic malignancies. The cumulative incidence of non-hepatic malignancies in F3 fibrotic fatty liver patients is 14%.





(source:internet, reference only)

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