July 15, 2024

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Do low-grade gliomas need surgery?

Do low-grade gliomas need surgery?


Do low-grade gliomas need surgery?  What are the symptoms of low-grade glioma?


What are the symptoms of low-grade glioma?

Low-grade gliomas (LGG) are a variety of primary brain tumors that usually occur in young patients. Compared with high-grade gliomas, they have a slower course of disease and long-term survival. Treatment options include observation, surgery, radiotherapy, chemotherapy or comprehensive treatment, and individualized treatment based on the tumor.


Pediatric low-grade glioma is a very common central nervous system (CNS) tumor in children. They account for 30% of all childhood CNS tumors.


What are the symptoms of low-grade glioma?

Symptoms associated with low-grade gliomas vary depending on the size of the tumor and its location in the brain. The age of the child and the growth rate of the tumor can also determine the symptoms experienced. Symptoms may include:

  + vision, hearing or speech problems

   + headache, especially in the early morning

  +Loss of balance or difficulty walking

  + Weakness, tingling or feeling change on one side

  + nausea and vomiting

  +unexplainable weight gain or loss


   + change in personality or behavior

  +head enlargement (infant)


Can low-grade gliomas heal on their own?

Many external neurosurgery experts pointed out that low-grade glioma is a type of glioma with relatively good therapeutic effect. The tumor growth rate is relatively slow, about 4-5mm per year, and the growth rate is relatively slow, but it is Malignant progression may become highly malignant glioblastoma, which can grow rapidly and cause death. Therefore, untreated low-grade gliomas may not have serious initial symptoms in the brain, but it is like a time bomb, and it may be life-threatening when it detonates.


The importance of low-grade glioma surgery

A low-grade glioma requires active treatment. Generally, surgical resection has a positive effect on prolonging survival time, rather than a simple biopsy. Biopsy surgery only takes a few specimens for diagnosis, which is basically the same as not removing the tumor. By comparing the prognosis of patients with low-grade glioma with simple biopsy and surgical resection, the role of surgical resection in low-grade glioma can be judged.

Studies have shown that for low-grade glioma, only biopsy is compared with surgical resection. The 5-year survival rate is 60% and 74%, respectively. The median survival time after resection is 14.4 years, and the survival time is approximately 2.5 times that of the former. This result shows that compared with simple biopsy, surgical removal of low-grade gliomas has a longer survival time and a lower rate of malignant progression. It also fully shows that surgical removal of low-grade gliomas can prolong the survival time of patients than simple observation. It has a positive effect. effect.

Due to the possibility of malignant progression of low-grade gliomas, surgical removal of low-grade gliomas can not only reduce the possibility of malignant progression, but also relieve the compression and space-occupying effect of low-grade gliomas on brain tissue. Therefore, the current low-grade gliomas Tumors are generally recommended for active surgical treatment, unless the tumor is in a special location that is not conducive to surgery, and only a few suspected low-grade gliomas choose the observation strategy.


(source:internet, reference only)

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