July 24, 2024

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Why could Nitroglycerin be fatal if used incorrectly?

Why could Nitroglycerin be fatal if used incorrectly?



Why could Nitroglycerin be fatal if used incorrectly?  The life-saving medicine for coronary heart disease myocardial ischemia: Nitroglycerin could be fatal if used incrorectly!

Buccal administration of nitroglycerin is only an emergency. To fundamentally solve angina pectoris, it is necessary to rely on comprehensive medication, stents, or bridges.

Nitroglycerin is a life-saving medicine for coronary heart disease! That’s right!

When angina pectoris occurs in some patients with coronary heart disease, if the angina pectoris is not relieved in time, the patient will be very painful and may induce risks such as myocardial infarction, arrhythmia, and sudden death.


Why could Nitroglycerin be fatal if used incorrectly?




First, life-saving medicine

When angina pectoris occurs, it is myocardial ischemia caused by cardiac vascular stenosis, and myocardial hypoxia causes angina pectoris. Nitroglycerin has the effect of dilating blood vessels. When the blood vessels are expanded, the stenosis of the blood vessels will be improved by ischemia and hypoxia, and angina pectoris will be improved. ease. If not relieved in time, severe angina can induce cardiac arrest.

Nitroglycerin is almost the only first aid for angina pectoris. It is effective for 93% of angina pectoris. It takes about 2 minutes to work. It is the most commonly used first aid for coronary heart disease.


Second, effective judgment

Angina pectoris usually takes 3 to 15 minutes each time. The standard of drug effectiveness:

1. Significant effect: angina pectoris disappeared or basically relieved within 3 minutes after medication.

2. Effective: The angina pectoris disappears or is basically relieved 3 to 5 minutes after the medication.

3. Ineffective: the angina pectoris is gradually relieved or not improved more than 5 minutes after the medication.

If it takes longer than 5 minutes to relieve, either the medicine itself is useless and it is not coronary heart disease angina pectoris; or the angina pectoris itself has a relatively short duration and has been relieved on its own.



Third, many friends left messages and rumors about nitroglycerin in acute myocardial infarction:

1. Acute myocardial infarction containing nitroglycerin is difficult to relieve symptoms;

2. Acute myocardial infarction is often accompanied by hypotension and shock, which will aggravate hypotension, such as acute inferior right ventricular myocardial infarction, such as acute extensive anterior wall myocardial infarction accompanied by cardiogenic shock, these conditions will cause nitroglycerin to be used If the condition is aggravated, nitroglycerin must not be used;

3. How do you judge it is an acute myocardial infarction? Chest pain must be an acute mood, right? Pulmonary embolism can also cause chest pain, and aortic dissection can also cause chest pain.


Fourth, common side effects:

After taking nitroglycerin, some people will experience:

1 Headache: It can occur immediately after the medication, and can be severe and persistent.

2 Occasionally, dizziness, weakness, palpitations and other orthostatic hypotension may occur, especially in patients who stand upright and immobilize.

3 Obvious hypotensive reactions can occur at therapeutic doses, manifested as nausea, vomiting, weakness, sweating, paleness, and collapse.

4 Syncope, flushing, drug eruption and exfoliative dermatitis have been reported.


Fifth, nitroglycerin taboo:

1. Acute inferior right ventricular myocardial infarction; at this time, there is no effect of taking anything, only to open the blood vessel as soon as possible is the king;

2. Severe anemia;

3. Glaucoma;

4. Increased intracranial pressure

5. Patients who are allergic to nitroglycerin;

6. Hypertrophic obstructive cardiomyopathy;

7. Hypotension;



He has a clear history of coronary heart disease. When angina pectoris occurs, he should take 1 capsule of nitroglycerin immediately, but he needs to see a doctor as soon as possible.

If it is effective, but the recurrent episodes can be swallowed again, in theory, the blood pressure is not low and you can continue to swallow it. The most extreme case of oral administration of nitroglycerin in the clinic is patients with three-vessel disease that cannot be stents and cannot be bridged. The patients often have no relief during the attack, and the patients have to have to take several times, often taking dozens of tablets every day.

For those with coronary heart disease, it is best to carry nitroglycerin with you. The validity period after opening the nitroglycerin is 3-6 months.

In short, buccal nitroglycerin is only an emergency. To fundamentally solve angina pectoris, it is necessary to rely on comprehensive medication, stents, or bridges.


(source:internet, reference only)

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