The 5th Cured AIDS Patient Emerges: Scientists Explain Recovery Process
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The 5th Cured AIDS Patient Emerges: Scientists Explain Recovery Process
Another AIDS patient has been cured, attracting global attention. 68-year-old American man Paul Edmund announced that, five years after a bone marrow transplant, his acute myeloid leukemia has been essentially cured, making him the fifth person globally to be cured of AIDS. To celebrate this medical miracle, his recovery case was published in the New England Journal of Medicine on February 15th.
In 1988, Edmund was first diagnosed with AIDS, and he began antiretroviral therapy in 1997 to suppress the HIV virus. However, the virus never disappeared, and its DNA remained latent in immune cells.
The turning point came with the bone marrow transplant. The donor who matched Edmund had a rare mutation in the CCR5 gene known as the delta 32 mutation.
This mutation is a congenital mutation that confers resistance to the HIV virus, and only about 1-2% of people have this mutation. After the surgery, Paul’s bone marrow and blood stem cells were completely replaced by healthy cells from the donor, and he has since shown no signs of leukemia or AIDS.
In March 2021, Edmund decided to stop taking antiretroviral drugs. After nearly three years of close monitoring, doctors confirmed that there was no trace of the HIV virus in his body.
Who are the 1st, 2nd, 3rd and 4th Cured AIDS Patient?
The 5th Cured AIDS Patient Emerges: Scientists Explain Recovery Process
(source:internet, reference only)
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