World First Lung Cancer Vaccine Begins Testing
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World First Lung Cancer Vaccine Begins Testing
The world’s first lung cancer vaccine has entered testing in several countries, including Spain, according to a report by Buenos Aires Economic News on August 24.
This medical milestone is considered by the scientific community to have groundbreaking potential, with hopes of saving hundreds of thousands of lives. Lung cancer claims nearly 1.8 million lives annually, making it the leading cause of cancer-related deaths worldwide. The low survival rate for advanced-stage lung cancer contributes to its high mortality.
The new vaccine, an mRNA (messenger ribonucleic acid) type, works by enabling the body to identify and destroy cancer cells while preventing their recurrence. Produced by the German company BioNTech, the vaccine is designed to treat non-small cell lung cancer, the most common form of lung cancer.
Named BNT116, the vaccine has entered Phase 1 clinical trials in seven countries: the United States, Germany, Spain, the United Kingdom, Poland, Hungary, and Turkey. A total of 130 patients have already been enrolled to receive the vaccine and undergo immunotherapy.
Similar to the COVID-19 vaccines, BNT116 uses mRNA technology. According to the U.S. National Cancer Institute, this type of vaccine “carries the genetic instructions needed to produce proteins, transferring this information from DNA in the cell nucleus to the cytoplasm where proteins are made.”
The vaccine works by presenting lung cancer tumor markers to the immune system, allowing the body to fight the cancer cells that express these markers. In essence, it serves as a form of “training” for the immune system. Unlike chemotherapy, this treatment enhances the immune system’s response without harming healthy cells.
University College London Hospitals (UCLH) is leading the trial in the UK. Professor Li Xiaoming, a consultant oncologist at UCLH, said, “We are entering an exciting new era of mRNA-based immunotherapy clinical trials for lung cancer treatment.”
Professor Li added, “The vaccine is easy to administer and can target specific antigens on cancer cells, then attack them.” Many experts agree that this technology represents the next significant phase in lung cancer treatment.
World First Lung Cancer Vaccine Begins Testing
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