Quitting Smoking Cuts Heart Risk by 50% While Reducing Smoking Offers Minimal Benefit 

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Quitting Smoking Cuts Heart Risk by 50% While Reducing Smoking Offers Minimal Benefit 

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Quitting Smoking Cuts Heart Risk by 50% While Reducing Smoking Offers Minimal Benefit 

A study presented at the ESC Congress 2024 on August 31 revealed that patients with stable coronary artery disease (CAD) can reduce their risk of major cardiovascular events by nearly 50% if they quit smoking at any time after their diagnosis.

In contrast, simply reducing the number of cigarettes smoked provides minimal cardiovascular benefits.

The international CLARIFY registry, which tracks patients with stable coronary artery disease, evaluated the impact of smoking status on cardiovascular events. The registry included 32,378 CAD patients.

The study analyzed the occurrence of major adverse cardiovascular events (MACE), defined as cardiovascular death or myocardial infarction during a 5-year follow-up period.

On average, patients were enrolled in the study 6.5 years after their CAD diagnosis: 41.3% (13,366) had never smoked, 46.2% (14,973) were former smokers, and 12.5% (4,039) were current smokers. Of those who were smokers at the time of diagnosis, 72.8% quit smoking within the following year, while 27.2% quit in subsequent years.

“The first year after diagnosis is a critical window for quitting smoking,” said Dr. Jules Mesnier of Bichat-Claude Bernard Hospital in Paris, the study’s lead author. “It’s essential to emphasize the importance of smoking cessation at the time of diagnosis and support patients in this challenge.”

Regardless of when they quit, CAD patients who stopped smoking after their diagnosis showed significant cardiovascular improvements, with a 44% reduction in MACE risk (adjusted hazard ratio [HR] 0.56; 95% confidence interval [CI] 0.42-0.76; P<0.001).

Compared to those who continued smoking, patients who reduced their smoking habit did not show a significant change in MACE risk (adjusted HR 0.96; 95% CI 0.74-1.26; P=0.78). Additionally, each additional year of continued smoking after a CAD diagnosis increased the risk of MACE by 8% (adjusted HR 1.08 per year; 95% CI 1.04-1.12).

While the risk of MACE significantly and rapidly decreases for those who quit smoking, even after years of cessation, their cardiovascular risk never reaches the level of those who have never smoked.

Dr. Mesnier concluded, “I like to tell my patients that it is never too early or too late to quit smoking, though the sooner they quit, the better for reducing cardiovascular risk. Simply cutting down on smoking isn’t enough. At every medical intervention, we need to deliver a brief and clear message emphasizing the necessity of quitting. Telling patients that they can cut their risk of major events or death in half—as we’ve shown here—is a powerful message.”

Measures to promote smoking cessation include brief advice, counseling, behavioral interventions, and pharmacotherapy.

Quitting Smoking Cuts Heart Risk by 50% While Reducing Smoking Offers Minimal Benefit 

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(source:internet, reference only)

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Important Note: The information provided is for informational purposes only and should not be considered as medical advice.