January 30, 2023

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What’s recurrence factors of glioma and How to treat it?

What’s recurrence factors of glioma and How to treat it?



What’s recurrence factors of glioma and How to treat it? There are a variety of treatment methods for glioma. Among them, surgery is the first choice, and radiotherapy, chemotherapy, traditional Chinese medicine, gene therapy, etc. may be supplemented after surgery.


A female elderly patient, had a sudden convulsion in June 1995. The hospital diagnosed a new glioma, and then underwent tumor resection, combined with X-knife radiotherapy after the operation, and the treatment effect was satisfactory.

In recent years, this patient has been uncomfortable. In August 2002, the convulsions reappeared, and the “Noli Knife” treatment was performed, but the effect was not satisfactory.

From discharge to December 2002, the patient’s left limb gradually became restricted in movement, and the tumor recurred and increased significantly on re-examination of CT. He needed another craniotomy, followed by a second tumor resection. The operation went smoothly and he recovered. better.

But 3 months later (March 27, 2003), the patient had convulsions again, and the CT scan showed that the tumor recurred again with intracranial metastasis.



What is the cause of the recurrence of glioma? What are the good measures for the treatment of this recurrent glioma? How to treat patients with tumor metastasis?

Glioma is one of the most common intracranial tumors, accounting for about 45% of all brain tumors. Glioblastoma occupies the first place among brain tumors due to its high incidence, high disability rate, and high recurrence rate. The average survival time of malignant glioma is about 18 months, and it is also one of the most difficult diseases in neurosurgery.

At present, there are a variety of treatment methods for glioma. Among them, surgery is the first choice, and radiotherapy, chemotherapy, gene therapy, etc. may be supplemented after surgery. Although there are many treatment methods available, it is difficult to achieve a complete cure for glioma. The prognosis of patients is related to many factors such as tumor type, size, pathological grade, growth location and choice of treatment methods.

As for the recurrence of glioma, because the tumor is infiltrating growth, it cannot be completely removed even under a microscope, which is the root cause of the recurrence. Generally speaking, tumors located in the important structures of the brain are more difficult to remove completely by surgery. Therefore, the curative effect is not very satisfactory, the tumor recurrence rate is high, and the treatment can only extend the survival period and improve the quality of life in the short term.

Judging from the above-mentioned patient’s situation, the patient’s two operations and radiotherapy have achieved good results. According to the patient’s current condition, the patient can be recommended to review the brain-enhanced magnetic resonance imaging, aiming to understand the scope of intracranial tumors and whether there are multiple metastatic lesions.

At the same time, take anti-epileptic drugs as needed to prevent undesirable consequences such as falling injuries during epilepsy. Since the most recent Noliknife treatment was in August 2002, it is not advisable to do radiotherapy again to avoid aggravation of the condition due to radiotherapy reactions. If the tumor has metastasized, treatment options should be made according to the location and type of the metastasis and the patient’s own condition. It can be treated with surgery, chemotherapy or comprehensive therapy, and certain effects can also be received.

The human nervous system is composed of the brain and spinal cord (called the central nervous system), cranial and spinal nerves (called the peripheral nervous system), and sympathetic and parasympathetic nerves (called the autonomic nervous system).

It is the highest organ of the human body, dominating all human life activities. In our daily diagnosis and treatment work, we deal with various diseases for patients with neurological diseases every day and answer questions related to their diseases. On this basis, we organize the common questions raised by disease categories. It aims to provide guidance and help for the vast number of patients with the nervous system to seek medical advice!


(source:internet, reference only)

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