April 25, 2024

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Protection of COVID-19 vaccines plummeted with the time of vaccination

Protection of COVID-19 vaccines plummeted with the time of vaccination

 

 

 


Protection of COVID-19 vaccines plummeted with the time of vaccination.  The biggest news in the past week is: The protection of Pfizer vaccine announced by the Israeli Ministry of Health has been reduced to 39%.

Let’s learn data first, and finally analyze the Israeli data.

 

 

 

A, the global COVID-19 epidemic: Continue to deteriorate


According to the New York Times Epidemic Tracker, the number of new cases in a single day worldwide has increased by 23% over the previous two weeks, reaching 530,000 per day; the number of deaths has increased by 25% over the previous period, reaching more than 9,800.

 

Protection of COVID-19 vaccines plummeted with the time of vaccination
(Source: New York Times Epidemic Tracker)

From the map of the COVID-19 epidemic, the biggest change this week is that the United States has returned to the country with the largest number of confirmed cases in a single day, with more than 50,000 new cases every day; followed by Brazil, Indonesia, the United Kingdom and India.


Protection of COVID-19 vaccines plummeted with the time of vaccination
(Number of infected cases in a single day on July 24. Source: Data World)

 

From an intercontinental point of view, only Asia and North America have sustained an increase in the number of new cases in a single day, while the epidemics in Europe, South America and Africa have all improved.


Protection of COVID-19 vaccines plummeted with the time of vaccination
(Changes in new cases in a single day. Source: Data World)


The epidemic in the United States has worsened than before.

In the past two weeks, the number of new cases in the United States has increased again by 172%, the number of hospitalizations has increased by 57%, and the number of deaths has increased by 19%.

The current new cases in the United States are mainly in states with low vaccination rates, and 99.5% of the deaths are unvaccinated.

Protection of COVID-19 vaccines plummeted with the time of vaccination

(Source: New York Times Epidemic Tracker)


By July 18, 2021, 56% of the U.S. population, 69% of adults aged 18 and over, and 89% of people 65 and over have received at least one dose of the vaccine.

 

 


B, vaccination: China’s  vaccination volume is far ahead


Vaccines are the only way to complete herd immunity and the most effective way to rescue humans from COVID-19.

Therefore, the world is rushing to vaccinate. But not everyone can get the vaccine.

As shown in the figure below, of the 3.8 billion vaccine doses that humans have received, China has vaccinated more than 1.5 billion doses. In the past week, China has vaccinated more than 13.04 million doses per day on average! Wow the world.

The proportion of vaccination in China has exceeded that of the United States and the EU.

(End of the epidemic competition. Screenshot source: Bloomberg)

 

 

However, global vaccination is still severely unbalanced. If according to the vaccination rate of each continent, Europe has the highest (82%), followed by North America, South America, Asia, Oceania and Africa (4.6%).

(Source: New York Times Epidemic Tracker)

 

 

 

 

C, varies with the time of vaccination: Declining vaccine protection

 

Israel was the first to vaccinate, and it became a demonstration of judging the protection of vaccines so as to adjust vaccination strategies in a timely manner.

 

In the first real-world study reported in Israel in February 2021, the Pfizer mRNA vaccine’s protection against infection with symptomatic COVID-19 was as high as 94%; by the latest report on July 24, the protection was reduced to 39%. What happened in just 5 months?

 

On February 24, 2021, the most well-known medical journal, the New England Journal of Medicine (NEJM), published the highly anticipated real-world protection data of Israel’s mRNA vaccine against COVID-19 (BNT162b2) after vaccination. The study found that the vaccine’s protection against symptomatic SARS-CoV-2 infection was as high as 94% 7 days after the second vaccination, which was very close to the 95% of the phase 3 clinical trial results.


The first real-world COVID-19 vaccine study was published in the top issue, and the observation of 596,000 vaccinators gave five key data


On July 8, 2021, the latest real-world study published by the Israeli Ministry of Health found that the Pfizer vaccine’s protection against symptomatic new coronavirus infections has been reduced to 64%.

 

On July 23, 2021, CNBC reported the latest results reported by the Israeli Ministry of Health, which is extremely worrying. The Israeli report shows that Pfizer/BioNTech’s mRNA vaccine has only 39% protection against symptomatic COVID-19 caused by the Delta mutant strain in Israel.


There is a bigger blow.


According to detailed data from the Israeli Ministry of Health, as of January 31, more than 1.8 million people were fully vaccinated. During the week of July 11-17, 1,181 of these people were infected with the COVID-19 virus. For 6 months For those who were fully vaccinated before, Pfizer vaccine’s protection against infection with symptomatic COVID-19 has dropped to 16%!

The protective power of Pfizer mRNA Covid-19 vaccine against symptomatic COVID-19 was 94% at the time of vaccination, and it was reduced to 16% within 6 months of vaccination.

Seeing this set of data, do you think that humans can still establish herd immunity against the new coronavirus?

  • The one who knows the vaccine situation best is Pfizer, which “exchanges vaccines for data”. 
  • Therefore, on July 8th, Pfizer publicly proposed to make preparations for intensified vaccination.
  • But it was immediately slapped by the US CDC and FDA: No need!
  • Pfizer has also been criticized by netizens for profiting.
  • Pfizer: Need a third shot of reinforcement; FDA+CDC: No need!

Now many people think that Pfizer only holds the first-hand data on Israel’s protection after vaccination, and can’t help but leak it out.

In the face of the new coronavirus, is this currently known as the strongest vaccine so weak?

On July 23, the data released by the Israeli Ministry of Health also showed that the Pfizer mRNA vaccine still has 88% protection against hospitalization of patients infected with COVID-19, and 91% protection against severe cases.

 

 

 

Expert Comments:

For non-professionals, these data are a bit convoluted. Let me briefly summarize:

  1. With the prolonged vaccination time, the protective power of Pfizer vaccine against COVID-19 has plummeted, from 94% at the time of vaccination to 16% after 6 months;
  2. However, the Pfizer vaccine can still significantly inhibit the development of severe illness in the infected person.
  3. For people who have been vaccinated, it means that the infection rate has increased, but the possibility of becoming seriously ill after infection is still extremely low; but because they are still prone to infection after vaccination, their family members who have not been vaccinated can no longer be effectively protected NS.
  4. For people who have not been vaccinated, it means that it is almost impossible to escape the infection. Because herd immunity cannot be established, the epidemic will only spread more wanton. The fatality rate of unvaccinated patients is still very high.
  5. Non-drug interventions, including wearing masks, maintaining social distancing, and gathering less, are still the most important means to prevent COVID-19 infection.

 

(source:internet, reference only)


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