Pfizer COVID-19 vaccine is 88% or 39% effective against Delta variant?
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Pfizer COVID-19 vaccine is 88% or 39% effective against Delta variant?
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Pfizer COVID-19 vaccine is 88% or 39% effective against Delta variant? Is the protection power 88% or 39%? The truth about Pfizer vaccine preventing the Delta mutant strain is here
In the past week, the Ministry of Public Health of the United Kingdom and the Ministry of Health of Israel respectively released real-world data on the prevention of Delta mutant strains by their own vaccines, but the two results are surprisingly different.
On July 21, 2021, the New England Journal of Medicine (NEJM) uploaded the public health department’s (PHE) vaccination data on the protection of the real world of Delta variants. This is the first vaccine published to be effective for the real world of the Delta mutant strain. Sexual research data.
Fully inoculated with Pfizer mRNA vaccine, the protection against symptomatic COVID-19 caused by the Delta mutant strain is 88%.
The first real-world study on the protection of vaccines against Delta mutant strains was published, and the results are mixed
On July 23, 2021, CNBC reported the latest results reported by the Israeli Ministry of Health, which is extremely worrying.
The Israeli report shows that Pfizer/BioNTech’s mRNA vaccine has only 39% protection against symptomatic COVID-19 caused by the Delta mutant strain in Israel.
Israel: In the face of the Delta mutant strain, Pfizer vaccine’s protection against infection is reduced to 39%
88% vs. 39%, which one is right?
As medical and biological researchers, we believe that these two figures are accurate. What we need to do is to analyze the specific data behind the numbers in order to have a correct understanding of vaccine protection.
We found more specific data from The Jerusalem Post, which has a strong guiding significance for our vaccination strategy.
First, the time difference between vaccination and re-infection.
As of July 23, the proportion of fully vaccinated in the UK was 54.15%, and the proportion of fully vaccinated in Israel was 61.13%. At first glance, the rates of complete vaccination between the two countries are almost the same.
But looking further, when the Israeli vaccination rate exceeded the current level of the UK (54.33%) on March 25, the vaccination rate in the UK was only 4.43%.
This means that 88.88% of fully vaccinated persons in Israel were vaccinated 4 months ago, while 91.82% of fully vaccinated persons in the UK were vaccinated within the last 4 months.
Do you remember Pfizer’s CEO’s advice on July 8th?
Pfizer suggested that a third dose should be prepared to boost the immunization, but it was immediately rejected by the US Food and Drug Administration and the Centers for Disease Control and Prevention.
Many people said that Pfizer was lustful at the time. In fact, Pfizer only knew the details of its vaccine: as the vaccination time was extended, the protection of the vaccine gradually decreased; because the level of neutralizing antibodies was rapidly decreasing.
The Israeli data just 2 weeks ago still had 64% protection; after two weeks, it dropped to 39%.
Pfizer: Need a third shot of reinforcement; FDA+CDC: No need!
This Israel report has once again confirmed this point.
According to data from the Israeli Ministry of Health, as of January 31, more than 1.8 million people were fully vaccinated. During the week of July 11-17, 1,181 of this group of people were infected with the new coronavirus, accounting for all new cases. 20% of it.
If the protection is calculated, it shows that for people who were fully vaccinated 6 months ago, the protection of Pfizer vaccine against infection with symptomatic COVID-19 has dropped to 16%!
Therefore, 88% of the protection of Pfizer vaccine in the United Kingdom is only because of its late vaccination time; 39% of the protection in Israel is only because of its early vaccination. The protection of fully vaccinated people 6 months ago has been reduced to 16%. .
Secondly, it is the age of the vaccinators in the two countries.
Both Israel and the United Kingdom took the lead in vaccinating medical staff and the elderly.
However, the majority of Pfizer vaccinations in the UK are young people, because the AstraZeneca vaccine was found to be related to fatal thrombosis that occurred in young people vaccinated.
In Israel, everyone is vaccinated by Pfizer, including the elderly, and they are vaccinated very early.
Breakthrough infections are more obvious in people 60 years and older, and this group has a lower immune function. The age groups of the observers are different, and the British observers are younger. Obviously, this is also one of the reasons for the difference in protection between the two countries.
(The proportion of vaccinations in different age groups, blue is Pfizer vaccine. Source: Lancet)
Third, it has something to do with the interval between two doses in the UK.
A study published by the University of Oxford last week showed that in terms of producing neutralizing antibodies, an interval of 8 weeks between the first and second doses of vaccine is a sweet spot, that is, it can induce higher levels of neutralizing antibodies.
Pfizer vaccine requires two doses, and the recommended interval between the two doses is 3 weeks. However, the practice in the UK when starting vaccination is to “prioritize the vaccination rate”, that is, get one dose first, and spread the second dose 4-12 weeks later, thereby allowing more people to get at least one dose of the vaccine.
Therefore, the interval between Pfizer vaccinations in the UK is better than that in Israel.
Expert Comments:
“Data tells the truth.”
When we take a closer look at the “UK 88% vs. Israel 39% protection” figure, the specific data behind it shows:
- The protective power of the vaccine is getting lower and lower as the time after vaccination is prolonged, and it is exact and significant;
- Priority should be given to intensive vaccination among the elderly and other susceptible groups;
- The interval between two doses of vaccination needs to be optimized. Currently, 8 weeks is appropriate.
This result also worries us about the first batch of medical staff who were vaccinated.
Most medical workers in the United States start vaccination between December 2020 and January 2021. At present, most people have been fully vaccinated for more than 6 months.
According to Israeli data, it means that for this group of medical workers, the vaccine’s protective power is only 16%. It is necessary and urgently needed to complete the research as soon as possible and take measures to replant when necessary.
As the vaccination time increases, everyone must re-examine the risk of breakthrough infection. Several medical scientists in the United States suggested that “remand mandatory requirements to wear masks indoors, regardless of whether they have been vaccinated”.
(source:internet, reference only)
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