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FDA approved 3rd dose (booster shot) of Pfizer and Moderna COVID-19 vaccine
FDA approved 3rd dose of Pfizer and Moderna COVID-19 vaccine . Ignoring WHO recommendations, the U.S. FDA officially approves the provision of a third dose of vaccine to certain populations.
U.S. Food and Drug Administration (FDA) officially approved the provision of a third dose of the COVID-19 vaccine to people with weakened immune systems.
On the evening of August 12, the FDA issued a statement stating that the authorization applies to vaccines produced by Monard and Pfizer. The booster injections are mainly targeted at organ transplant recipients or people whose immune systems are similarly damaged. However, the FDA emphasized that other fully vaccinated people do not need to receive booster shots now.
The day before, a study in the New England Journal of Medicine showed that additional doses of Monard vaccine significantly increased the level of antibodies against the new coronavirus in organ transplant patients. The results of the study showed that only 18% of patients who received a placebo injection instead of a third injection showed the required antibody levels.
The booster shot injection is especially important for transplant patients and other people with weakened immune systems. A number of studies have shown that some drugs and diseases can weaken the effect of the COVID-19 vaccine. Rochelle Varensky, director of the US Centers for Disease Control and Prevention, said at a press conference that immunocompromised people account for about 3% of adults.
White House chief medical adviser Anthony Fauci said on NBC’s “Today” program that only those with weakened immune systems can get booster shots. For other vaccinated groups such as the elderly, data is still being collected to determine whether or when the vaccine protects them “below the critical level.”
At this moment, we will not provide booster shot to other people except those whose immunity is compromised, but we will follow these people very carefully, and if they really need it, we will be ready to provide them with booster shot. Fauci also said that everyone needs a third dose of vaccine.
Prior to this, countries such as Israel, Germany, and France all provided enhanced injections for vulnerable groups. Other countries, including Russia, Hungary and the United Arab Emirates, are offering a wider range of third shots. The United Kingdom will also begin to intensify injections for vulnerable groups next month.
According to US CDC data, approximately 60% of eligible Americans 12 years of age and older have been vaccinated. Although the injection rate is rising after a sharp drop from its peak in mid-April, the Biden administration is urging people to get vaccinated.
An advisory committee of the CDC will also discuss the booster dose of the COVID-19 vaccine for immunocompromised patients on the 13th local time.
Recently, the COVID-19 pneumonia epidemic in the United States has rapidly deteriorated, and the number of daily confirmed cases has rebounded sharply. The Biden administration announced last month that it had received 200 million doses of Pfizer vaccine and expanded its total order to 500 million doses.
Pfizer said that the effectiveness of the company’s COVID-19 vaccine is declining over time. Studies have shown that after the second dose of Pfizer’s vaccine is completed, the effective rate can reach up to 96%, but it drops to 84% after 4 to 6 months. Moderna also believes that it is necessary to inoculate a booster shot.
Previously, the World Health Organization called for a moratorium on the intensified injection of the COVID-19 vaccine until more people in the world received the first shot.
On August 12, the top international publication Scince published online detailed data on the efficacy of Moderna’s COVID-19 mRNA vaccine against different mutant strains, showing that the vaccine has protective efficacy against different mutant strains, reaching the peak at the second dose of vaccination, and the second vaccination After 6 months, the needle still has protective effect, but it is already at a low level. The lowest protective effect is not Delta, which is currently raging around the world, but B.1.351 (Beta).
At present, Moderna is studying the effect of the third dose of mRNA vaccine on the efficacy and breadth of antibodies. Early results show that the third dose of mRNA vaccine has a significantly enhanced protective effect on D614G and other mutant strains.
(source:internet, reference only)