- Why are vegetarians more likely to suffer from depression than meat eaters?
- Small wireless device implanted between skin and skull helps kill cancer cells
- Will the mRNA vaccine that can cure cancer come out near soon?
- Allogeneic T-cell therapy set for landmark first approval
- Boston University denies that the new COVID strain they made has 80% fatality rate
- A new generation of virus-free CAR-T cell therapy
Disease-related single cell database
Disease-related single cell database. For sequencing, single-cell sequencing is a very popular sequencing technology. Simply put, single-cell sequencing technology is to sequence every cell.
Compared with the previous RNA-seq, we are actually testing all the RNA in a certain tissue. Since there are many cells in a tissue, and these cells are not necessarily all tumor cells, we say The gene expression results obtained by sequencing may not be the expression of the tumor. At this time, if single-cell sequencing is performed, the expression of genes in each cell will be detected, so that the results of the analysis will be more accurate.
For single-cell sequencing, there have been many articles that have done related tests, so many single-cell sequencing data have been published, and there are many single-cell-related databases. Today I will introduce to you a disease-related single-cell sequencing database sc2disease[http://easybioai.com/sc2disease/home].
Compared with many other single-cell analyses, this database is only used to analyze which genes are different between diseased cells and normal cells. So you can use it if you have this requirement.
Background data set introduction
This database is a collection of publicly published single-cell sequencing data. Use the same process to analyze the difference between diseased cells and normal cells.
Because the current single-cell sequencing data is relatively small. Therefore, this database has not yet been able to analyze cells that affect diseases or tissues. At present, only these diseases are included in this database. So there are children’s shoes that are researching these diseases can try to use them.
Compared with other databases, the use of this database is more like a retrieval function and download function for analysis results. The author is using the same process to analyze the current single-cell data. Finally, the expression of genes in different diseased cells and normal cells can be obtained. Compared to us, this database is used to retrieve these results.
So this database provides two main functions
Browse: You can observe the results of all data in the database at once
Search: You can search based on the gene, disease and cell type you want
In addition to the above two functions, the database also provides a data download function. Using this function, we can download all the results of this database analysis. This makes it easy for us to conduct our own custom search.
Database usage scenarios
The above is the main function of this database. First of all, if the disease you are researching is included in this database, you can use this database to query if you want to further check the expression of a certain gene in tumor cells.
(sourceinternet, reference only)