What is the cause of ankylosing spondylitis? 

What is the cause of ankylosing spondylitis? 

What is the cause of ankylosing spondylitis?   External infections Some scholars have discovered after extensive observation that many male patients with ankylosing spondylitis have prostatitis.

Nowadays, ankylosing spondylitis has gradually become a high-risk disease among young people, and few people can detect the disease in an early stage. Even if the condition is discovered, it may be ignored because of its mild condition. Ankylosing spondylitis doctors believe that early treatment of ankylosing spondylitis is very important. First of all, let’s understand the cause of ankylosing spondylitis.

Causes of ankylosing spondylitis

Autoimmune deficiency

The serum complement of patients with ankylosing spondylitis is higher than that of ordinary people. Most of the cases have IgA type moisture-like factor, serum C4 and IgA levels are significantly increased, there is circulating immune complex (CIC) in the serum, but the antigenic nature is not determined. Therefore, this is one of the causes of ankylosing spondylitis.

Genetic problems

According to the survey, the incidence rate among relatives of patients with ankylosing spondylitis is about 30 times higher than that of ordinary people. Some studies have found that multiple pairs of twin brothers have had ankylosing spondylitis. The positive rate of HLA-B27 (human leukocyte antigen B27) in patients with ankylosing spondylitis is as high as 90% or more, but 4% to 6% of the normal population are HLA-B27-positive. Therefore, those who are HLA-B27-positive may not necessarily suffer from rigidity. For sexual spondylitis, doctors never diagnose the disease solely on the basis of HLA-B27 positive. It also shows that there are other factors that play a role in the pathogenesis.

External infection

After a lot of observations, some scholars found that many male patients with ankylosing spondylitis have prostatitis. In addition, some studies have found that the incidence of ulcerative colitis and localized enteritis in patients with this disease is higher than that of ordinary people, so it is speculated that the pathogenic factor may be infection.

Other reasons

The incidence of the disease is also related to age, physical fitness, malnutrition, climate, water and soil, humidity and cold. Others include trauma, parathyroid disease. Upper respiratory tract infection, local purulent infection, etc., may have a certain relationship with this disease, but the evidence for these factors is insufficient.

Introduction to the causes of ankylosing spondylitis. Through the introduction of the above content, I believe that everyone has a certain understanding of the causes of ankylosing spondylitis. Sometimes in the treatment of compulsory spine, it is necessary to take timely and effective treatment methods according to their own causes and conditions. Get treatment. I hope the above content can help you, and I wish you good health.

(source:internet, reference only)

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