July 22, 2024

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Study finds the link between low vitamin D levels and Long-COVID

Study finds the link between low vitamin D levels and Long-COVID


Study finds the link between low vitamin D levels and Long-COVID.


People with low vitamin D levels have an increased risk of Long-COVID, according to findings presented at the 25th European Congress of Endocrinology in Istanbul. Findings suggest that vitamin D levels should be checked in patients after infection with COVID-19.


Study finds the link between low vitamin D levels and Long-COVID


Long-COVID, also known as post-COVID-19 syndrome, is a relatively new health condition characterized by symptoms of COVID-19 lasting more than 12 weeks after initial infection. Studies have shown that it occurs in 50%-70% of patients hospitalized with COVID-19. Despite the prevalence of COVID-19, our understanding of it is still limited.


Low vitamin D levels are a risk factor for worsening illness (eg, intubation, mechanical ventilation, or death) in hospitalized patients with COVID-19, but the role of this factor in prolonged COVID has not been adequately studied.


In the study, supported by the company Abiogen Pharma SpA, researchers at Vita-Salute San Raffaele University in Milan and IRCCS San Raffaele Hospital examined 100 long-COVID and non-COVID patients aged 51-70.

They measured vitamin D levels when they were first admitted to the hospital for COVID-19 and six months after discharge, and found that patients with chronic COVID had lower levels of vitamin D compared with patients without chronic COVID.

At a six-month follow-up, the results were even more pronounced among patients who experienced symptoms of “brain fog” such as confusion, forgetfulness and difficulty concentrating.


The researchers’ study included patients without any bone disease, as well as patients who were only hospitalized with COVID-19 but not in the intensive care unit (ICU).

They matched the two groups of patients with and without long-term COVID with respect to age, sex, pre-existing chronic diseases, and severity of COVID-19.

Lead researcher Professor Andrea Giustina said: “Previous studies on the role of vitamin D in prolonged COVID have been inconclusive, mainly due to many confounding factors.

Our study is highly controlled and helps us to better understand the role of vitamin D deficiency in prolonged COVID and to identify possible links between vitamin D deficiency and prolonged COVID”.


While Professor Giustina acknowledges that larger studies are needed to confirm the link, he and his team are now focusing on finding out whether vitamin D supplementation reduces the risk of developing COVID. “Our study shows that COVID-19 patients with low vitamin D levels are more likely to develop COVID-19, but it is unknown whether vitamin D supplementation can improve symptoms or reduce this risk entirely.”






Study finds the link between low vitamin D levels and Long-COVID

(source:internet, reference only)

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