HPV clinical treatment has limitations

HPV clinical treatment has limitations. HPV virus is a gradual process from infection to cervical cancer. Does HPV infection definitely cause cervical cancer? How to prevent and treat HPV infection? With these questions in mind, “Science China” interviewed Professor Li Fang from Dongfang Hospital of Tongji University (formerly the Cervical Department of Shanghai First Maternal and Child Health Hospital).

HPV virus is a gradual process from infection to cervical cancer. During this period, the lesion is in a state of change, and the infection may continue, or it may remain unchanged or even disappear naturally. In this process, if appropriate interventions are given, the low-grade lesions can be relieved or cured, and the occurrence of cervical cancer can be prevented.

According to Li Fang, clinicians usually use a variety of testing methods to make judgments during outpatient clinics. If they are newly infected patients, they still hope to clear the virus by their own immunity, and if they have been infected for one or two years, they will rely solely on their own. Immune function cannot be eliminated. At this time, they would recommend the patient to receive treatment.

“According to the 2010 U.S. Centers for Disease Control Human Papillomavirus Infection Treatment Guidelines, HPV infection can be left untreated. However, in terms of clinical practice, once HPV infection is discovered, patients have a heavy mental burden and are very anxious. Some patients After discovering that I was infected with HPV and diagnosed as a precancerous lesion, I even considered that my life would be threatened. Some patients with low-grade infections would also be too anxious to sleep. Therefore, we will also provide treatment at the request of the patient.” Li Fang analyzed. .

At present, the clinical treatment methods for cervical precancerous lesions mainly include laser, freezing, microwave, photodynamic, external corrosive, interferon, LEEP surgical resection, etc.

Surgical resection therapy, including LEEP, laser, etc., can cure most precancerous lesions, and remove local lesions of the cervix. However, for a considerable number of patients, surgical resection therapy cannot eliminate persistent HPV infection, and can cause a decrease in cervical elasticity, which may affect natural delivery.

(source:chinanet, reference only)

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