How are cancer cells in breast cancer different from healthy cells?

How are cancer cells in breast cancer different from healthy cells? Introduction to the level of cancer cells in breast cancer, how is it different from healthy cells?

The classification of breast cancer cancer cells is to confirm the formation and development of cancer cells. 

A grade is a “score” that tells you how the appearance and growth pattern of cancer cells differ from normal, healthy breast cells. Your pathology report will rate the cancer on a scale of 1 to 3:

• Grade 1 or low grade (sometimes called well differentiated): Grade 1 cancer cells look slightly different from normal cells. They grow in a slow, well-organized pattern. Not many cells are dividing to make new cancer cells.
• Grade 2 or intermediate/moderate (moderately differentiated): Grade 2 cancer cells do not look like normal cells and grow and divide slightly faster than normal.
• Grade 3 or high-grade (poorly differentiated): Grade 3 cells look very different from normal cells. They grow rapidly in a chaotic pattern, and many divide to produce new cancer cells.

Having low-grade cancer is a milder sign. But keep in mind that higher-grade cancers may be more susceptible to treatments such as chemotherapy and radiation therapy than low-grade cancers. These treatments target rapidly dividing cells.

Be careful not to confuse grade with breast cancer stage, which is usually expressed as a number between 0 and 4 (usually using Roman numerals I, II, III, IV). The stage is based on the size of the cancer and the extent to which it has (or has not) spread to its original location in the breast.

What’s Breast cancer?

The female breast is composed of skin, fibrous tissue, breast glands and fat. Breast cancer is a malignant tumor that occurs in the epithelial tissue of the breast. 99% of breast cancers occur in women, while men account for only 1%.

The breast is not an important organ for maintaining human life activities. Breast cancer in situ is not fatal; however, because breast cancer cells lose the characteristics of normal cells, the connections between cells are loose and easy to fall off. Once the cancer cells fall off, the free cancer cells can spread throughout the body with the blood or lymph fluid, forming metastases, and endangering life. Breast cancer has become a common tumor threatening women’s physical and mental health.

The global incidence of breast cancer has been on the rise since the late 1970s. One in eight women in the United States will develop breast cancer in their lifetime. China is not a country with a high incidence of breast cancer, but it should not be optimistic. In recent years, the rate of increase in the incidence of breast cancer in China is 1 to 2% higher than that of countries with high incidence.

Breast cancer has become a major public health problem in the current society. Since the 1990s, the global breast cancer mortality rate has shown a downward trend. The reason is that the development of breast cancer screening has increased the proportion of early cases; the second is that the development of comprehensive breast cancer treatment has improved the efficacy. Breast cancer has become one of the solid tumors with the best curative effect.

(source:internet, reference only)

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