December 8, 2022

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Why do patients with cerebral infarction need to take a thromboelastogram?

Why do patients with cerebral infarction need to take a thromboelastogram?


Why do patients with cerebral infarction need to take a thromboelastogram?  During the treatment of cerebrovascular patients, the doctor often asks the patient to take a thromboelastogram. Today we will learn about the “thromboelastogram”.

Why do patients with cerebral infarction need to take a thromboelastogram?

 

What is a thromboelastogram?

Thromboelastography (TEG) is a test item that studies the dynamic changes of blood coagulation.

It simulates the entire process of blood coagulation in the human body in vitro, including the blood coagulation process and the fibrinolysis process, and intuitively shows the entire dynamic change of coagulation.

Common blood tests 2 including prothrombin time can only reflect a certain stage or a certain coagulation product in the coagulation process.

However, thromboelastography can comprehensively assess the coagulation status of patients, clearly know the risk of ischemia and bleeding, and whether the human body has antiplatelet drug resistance, so as to effectively predict the occurrence of heart disease, stroke, hyperlipidemia, hypertension, diabetes, etc. in the normal population. Risks can also be screened for patients taking aspirin or clopidogrel, whether the drugs are effective.

 

Why do we need to detect thrombus elasticity map?

Assess coagulation status

It is more accurate and comprehensive to clarify ischemia and bleeding risk than traditional coagulation function testing.

Guide component transfusion

Perform reasonable and effective clinical blood transfusion by evaluating blood coagulation function and the cause of bleeding.

Reflect the efficacy of antiplatelet drugs

It has been clinically found that some patients with acute cerebral infarction also regularly take aspirin, clopidogrel and other antiplatelet drugs, but there are still problems of recurrence of cerebral infarction, suggesting there may be drug resistance. Thromboelastography can reflect the efficacy of antiplatelet drugs.

 

Simply put: is to test whether the aspirin or clopidogrel you are taking is effective? Which one is more effective? So choose medication.

The examination of thromboelastography is of great significance and value for the following diseases:

  • Thrombotic diseases: deep vein thrombosis, pulmonary embolism, cerebral infarction, coronary heart disease, etc.
  • Platelet abnormalities
  • Coagulation factor deficiency disease
  • Fibrinolytic diseases

The main indicators of thromboelastography are:

①Reaction time (R) means that there is no fibrin formation in the tested sample

②Coagulation time (K) indicates that fibrin begins to form in the tested sample, which has a certain degree of firmness

③The widest distance (MA) of the curves on both sides of the figure indicates the maximum amplitude of thrombosis

④The thrombus elasticity graph (ε) shows the elasticity of the thrombus

⑤Maximum solidification time (m), which means the time from solidification time to maximum amplitude

 

Specific blood collection:

Smoking and strenuous activities should be avoided before blood collection.


Sum up:

Thromboelastography can monitor the prethrombotic state and effectively predict the risk of heart disease, stroke, hyperlipidemia, hypertension, diabetes, etc. in the normal population.

It can be judged in time whether the antiplatelet drugs taken are effective.

Is a good helper for clinicians!

 

(source:internet, reference only)


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