April 21, 2024

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Endocrine drug Exemestane: Side effects for breast cancer patients

Endocrine drug Exemestane:  Side effects for breast cancer patients


Endocrine drug Exemestane Side effects for breast cancer patients.  

Breast cancer is like a long sword. It not only stabbed the patient mercilessly, but also brought endless pain and trouble to the patient.

For most patients, although most breast cancers are hormonal breast cancers with a good prognosis, many patients require continuous endocrine therapy for several years after surgery.


Some drugs not only need to be taken for several years, some drugs can also have side effects, which is also the most troublesome thing for patients.

Next, let’s take a look at the side effects of exemestane in breast cancer drugs?


Endocrine drug Exemestane: Side effects for breast cancer patients




Let’s take a look at the effects of exemestane and its side effects

Exemestane is an irreversible steroidal aromatase inactivator under the trade name of Sulai, Estetan, Arnosine, etc.

It is similar in structure to its natural substrate androstenedione, and is combined with its active site.

Inactivate it, thereby reducing the level of estrogen in the body.

Because the growth of cancer cells depends on the effects of estrogen, the selective treatment of postmenopausal hormone-dependent methods by inhibiting aromatase to prevent estrogen production.


The side effects of exemestane mainly include bone and joint pain, hot flashes, fatigue, headache, insomnia, etc.

Because the main effect of exemestane is to reduce estrogen in the body, and this less estrogen reaches bone cells, it will As a result, bones become thinner and brittle, and the risk of fractures increases.


If the bones in important parts are broken, it will be a serious risk to the patient’s life.

Therefore, during the period of taking this drug, the bone density test should be carried out regularly.

If the bone density loss is severe, other drugs should be changed.

During this period, the patient can also Take calcium supplements or eat some calcium-rich foods, such as milk, dried shrimps, kelp, peanuts, tofu, vegetables, etc.; proper sun exposure and proper physical exercise.


The above is the introduction about the side effects of the endocrine drug exemestane for breast cancer patients.

Bone fluid is the main side effect of this drug.

Patients should check the bone density regularly during the medication period. If any abnormalities occur, they should see a doctor and receive appropriate treatment.

In addition, it is also necessary to establish a good lifestyle, maintain a good mood, and follow up regularly.





Endocrine drug Exemestane:  Side effects for breast cancer patients

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