June 22, 2024

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Parents must see:  Rotavirus vaccine can prevent baby’s diarrhea!

Parents must see:  Rotavirus vaccine can prevent baby’s diarrhea!


Parents must see:  Rotavirus vaccine can prevent baby’s diarrhea!   Speaking of infant diarrhea, parents and mothers must have the most say. Infant diarrhea is a common disease of babies and one of the most difficult diseases for parents and friends to deal with. It is the main cause of malnutrition, growth and development disorders and even death of infants and young children. one of the reasons! 

Among the many causes of infantile diarrhea, rotavirus diarrhea is the most common one. Today I will share with you the knowledge of rotavirus for your reference.

Parents must see:  Rotavirus vaccine can prevent baby's diarrhea!


1. What is rotavirus diarrhea?

Rotavirus is the pathogen that causes severe dehydration and diarrhea in infants and young children. It mostly occurs in infants and young children between 6 and 24 months. Approximately 52,700 children die from rotavirus infections worldwide each year, accounting for approximately 1% of the total deaths caused by diarrhea. /3, is the second leading killer of children under 5 years of age. Almost everyone has been infected by rotavirus between the ages of 2 and 3! image


After each infection, the human immunity will gradually increase, and the impact of subsequent infections will be lessened, so adults are rarely affected by it. Compared with younger babies, older children, and adults, rotavirus infections are more serious in children aged 3 to 24 months.

After infants and young children are infected with rotavirus, the incubation period is 1 to 3 days, and they often have fever and upper respiratory tract infection symptoms. Vomiting often occurs in the first 1 to 2 days of illness, followed by diarrhea, stool frequency and water, showing light watery or egg-like stools, with a small amount of mucus, and no fishy smell. Severe cases have symptoms of dehydration, even acidosis and electrolyte disorders! In severe cases, multiple organs are often damaged, leading to multiple system diseases such as nerves, breathing, heart, liver and gallbladder, and blood!

Rotavirus usually has a high incidence in autumn and winter. It is usually sporadic or small epidemic. It is transmitted through the fecal-oral route, and it can also cause disease through respiratory tract infection in the form of aerosol.

2. How to prevent rotavirus diarrhea?

There is currently no specific medicine for rotavirus. In the face of acute diarrhea caused by rotavirus infection, methods such as prevention and correction of dehydration, rational medication, dietary adjustment, and prevention of complications are usually adopted. The promotion of rehydration therapy has indeed reduced the mortality rate of diarrhea. However, rotavirus-related deaths continue to appear. Before the advent of the vaccine, the number of rotavirus infections in the United States was about 2.7 million, causing an economic burden of about 1 billion US dollars!

The protection provided by natural immunization and other measures to improve public health (including the provision of clean food and water) cannot prevent diseases as effectively as vaccines. Only through the widespread use of safe, economical and effective vaccines can the morbidity and mortality caused by rotavirus infection be truly reduced, and the burden of rotavirus disease can be reduced!


3. Some questions about rotavirus vaccine


Q1: What is a rotavirus vaccine?

A1: The rotavirus vaccines currently on the market in China  are mainly oral five-valent reassortant rotavirus live attenuated vaccine and oral rotavirus live vaccine (monovalent).

The oral pentavalent reassortant rotavirus live attenuated vaccine is an oral pentavalent live attenuated vaccine containing 5 human-bovine rotavirus reassortants, and is obtained by culturing Vero cells. The five reassortant rotaviruses expressed the outer capsid protein VP7 or adhesion protein VP4 of the parental strain of human or bovine rotavirus.

The oral rotavirus live vaccine is made by inoculating newborn calf kidney cells with the attenuated rotavirus LLR strain, culturing, harvesting the virus liquid and adding suitable stabilizers.

Q2: What is the role of rotavirus?

A2: Rotavirus vaccine can stimulate the body to produce rotavirus gastroenteritis in children caused by group A or serotypes G1, G2, G3, G4, G9.

Q3: Who is suitable for rotavirus vaccination?

A3: The oral five-valent reassortant live attenuated rotavirus vaccine is suitable for infants from 6 weeks to 32 weeks of age; the oral live rotavirus vaccine is mainly used for infants from 2 months to 3 years old.

Q4: What is the vaccination procedure for rotavirus vaccine?

A4: A total of 3 doses of oral pentavalent reassortant live attenuated rotavirus vaccine. The first dose should be taken at 6-12 weeks of age. The interval between each dose is 4-10 weeks. The third dose should not be later than 32. Zhou age. Live oral rotavirus vaccine should be taken once a year.

Q5: Are there any restrictions on diet before and after rotavirus vaccination?

A5: Because it is an oral live vaccine, be careful not to drink hot water or warm milk 30 minutes before and after vaccination. In addition, babies with low immune function are not suitable for vaccination.

Q6: If the vaccine is spit out by the baby, do I need to re-vaccinate it?

A6: Since no research has been conducted on this situation in clinical trials, supplementary vaccination is not recommended. The remaining doses of vaccination should be completed in accordance with the subsequent immunization procedures.

Q7: Who should be cautiously vaccinated against rotavirus?

A7: Children with severe combined immunodeficiency disease may develop gastroenteritis after vaccination, including severe diarrhea and prolonged detoxification time of vaccine strains. In addition, infants with a history of intussusception are also contraindications for this vaccine.

Facing the rotavirus that specifically attacks babies, do parents and moms feel the power of rotavirus vaccine?

Yes, only by vaccination against rotavirus can we better prevent rotavirus infection! It is worth noting that within the age range specified in the instructions, the sooner the vaccination is, the better!

I hope that this knowledge sharing will prevent more babies from the threat of rotavirus and protect the health of more infants and young children!

(source:internet, reference only)

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