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Five basic treatments to prevent kidney disease to develop into uremia
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Five basic treatments to prevent kidney disease to develop into uremia. As long as we pay attention to these five basic treatments, it is difficult for kidney disease to develop into uremia!
If kidney disease can be detected early and the following five basic treatments are important, it is difficult for kidney disease to develop into uremia.
The proportion of uremia is not high or kidney disease is not easy to progress to uremia. Chronic kidney disease is not easy to become uremia. The reasons are many, including most kidney diseases are not serious, popularization of knowledge of kidney disease, emphasis on health examinations to detect kidney disease early, and more patients with kidney disease can standardize treatment and continue to suffer. New technologies or new therapies are promoted and applied, etc.
Therefore, if kidney disease can be detected early and the following five basic treatments are important, it is difficult for kidney disease to develop into uremia.
1. Actively prevent and treat infectious diseases
Infection is not only the cause of chronic kidney disease, but also the inducement or aggravating factor of chronic kidney disease.
Chronic pyelonephritis caused by repeated urinary tract infections can gradually develop into uremia; hepatitis B-related nephritis caused by hepatitis B virus infection may also develop into uremia; nephrotic syndrome complicated by colds or upper respiratory tract infections can cause renal failure, even rapid It develops into uremia; patients with chronic kidney disease 1-2 or 3-4 stages complicated by infections can quickly increase blood creatinine to the level of uremia in a short period of time; and so on.
Active prevention and treatment of various infectious diseases, including viral infections or bacterial infections, can prevent or reduce the occurrence of kidney disease, thereby avoiding or preventing the development of uremia. Targeted use of antiviral drugs or antibiotics can achieve this goal.
2. Treatments to reduce urine protein
Elevated urine protein is not only the main manifestation of kidney disease, but also an independent risk factor for the progressive progression of chronic kidney disease. Treating patients with kidney disease to lower urine protein can not only reduce the loss of nutrients, but also prevent the progression of chronic kidney disease. You can choose different protein-lowering drugs according to different conditions.
Such as glucocorticoids (such as methylprednisolone), immunosuppressants (such as tacrolimus), cytotoxic drugs (such as cyclophosphamide), biological agents (such as rituximab), sartan/pril drugs (Such as Losartan), statins (such as Atorvastatin), Liegliflozin (such as Enpagliflozin), Chinese medicine, etc.
These protein-lowering drugs can be used alone or in combination according to the condition. As long as the urine protein can be lowered, chronic kidney disease will be more difficult to develop.
3. Treatment to control blood pressure up to standard
Hypertension, nephropathy, chronic renal failure, and uremia are closely related, that is, hypertension can cause nephropathy, chronic renal insufficiency is more likely to be associated with hypertension, and chronic kidney disease with hypertension is more likely to develop in the direction of uremia. , That is, hypertension is also an independent risk factor for the progression of chronic kidney disease.
Therefore, controlling blood pressure to reach the standard has become the basic treatment for patients with kidney disease. Patients with kidney disease with normal renal function have many choices of antihypertensive drugs. The chemical names of the medicines include “sartan” (such as telmisartan), “pril” (such as peridopril), and “dipine”. “(Such as amlodipine), “lohr” (such as metoprolol) and “oxazosin” (such as terazosin) can be selected.
But the first choice for antihypertensive drugs, most of them are sartan, pril or dipine drugs, especially sartan or pril drugs, they can not only lower blood pressure, but also reduce the patient’s urine protein, it can be described as two birds with one stone.
4. Treatment to correct hyperglycemia
Nowadays, diabetic nephropathy is the main cause of chronic renal failure and uremia. Due to poor lifestyle and eating habits, people are more likely to have elevated blood sugar, which can cause diabetes and diabetic nephropathy. Therefore, the treatment of correcting hyperglycemia is also the basic treatment to avoid or prevent the development of kidney disease into uremia.
Nephropathy patients with normal glomerular filtration rate have elevated blood sugar or diabetic nephropathy, and there are many types of hypoglycemic drugs that can be selected, such as metformin, acarbose, litazone drugs (such as pioglitazone), and liptin drugs ( Such as linagliptin), gligliflozin drugs (such as enpagliflozin), sulfonylureas (such as gliquidone), glinide drugs (such as repaglinide) and insulin drugs (such as door Winter insulin 30R), etc., except for a few types of hypoglycemic drugs such as insulin and glinide that are not restricted by the decline in glomerular filtration rate, the choice of other hypoglycemic drugs must be aware of the severity of the patient’s renal failure.
5. Treatment of hyperuricemia
As people’s living conditions get better and better, coupled with lack of exercise, hyperuricemia is the “fourth highest” after the “three highs”, and hyperuricemia can also cause kidney disease, that is, hyperuricemia. Symptomatic nephropathy, which is tubulointerstitial damage caused by high uric acid.
In addition, chronic kidney disease can also appear or be complicated by hyperuricemia, which in turn can harm the kidneys. Therefore, whether it is primary hyperuricemia, concurrent or secondary hyperuricemia, uric acid-lowering therapy is also the basic treatment for this type of disease.
There are three main types of drugs used to treat hyperuricemia: one is drugs that promote uric acid excretion, such as benzbromarone; the other is drugs that inhibit uric acid production, such as febuxostat and allopurinol; and the third is alkali Urine drugs, such as sodium bicarbonate and potassium sodium citrate. It can be used according to kidney function.
If you can pay attention to the above five indicators and actively treat or correct them to a reasonable range, the prognosis of most patients with kidney disease will not be bad.
Five basic treatments to prevent kidney disease to develop into uremia
(source:internet, reference only)