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A new COVID-19 variant with about 35% fatality rate is coming
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A new COVID-19 variant with about 35% fatality rate is coming. The fatality rate is as high as 35%! A new variant is here, more fierce than Delta variant, antigen drifting, causing antibody failure!
A new variant of the COVID-19 virus has come out, which is more fierce than the Delta variant, with antigenic drift and a fatality rate of as high as 35%!
New variant antigen drifts, fatal up to 35%
The people are still discussing Delta variants, but the COVID-19 variant, which is more aggressive than the Delta variant, will hit the world with a fatality rate of 35%. This new variant of the COVID-19 virus is just named the SARS-CoV-2 variant.
This new variant was discovered by the British Government Emergency Advisory Group after studying the existing mutant strains of the new coronavirus and its evolutionary path. The new coronavirus may have “antigenic drift” mutations in the future-that is, when the virus mutates. To a certain extent, the previous antibodies no longer work, resulting in a further increase in infection rates and mortality.
The team’s scientific advisers warned that this higher-fatal mutation “almost certainly will happen to some extent”, and that the fatality rate of this mutant strain can be as high as 35%.
According to the latest report from the Latin American News Agency, a study published on July 29 by the preprint open access database BioRxiv pointed out that the lambda variant of the COVID-19 virus is not only highly contagious, but may also escape Neutralizing antibodies.
According to the report, a group of Japanese scientists proposed that the spike protein of this variant strain, which they discovered in Peru and is now widely spread in at least 30 countries, is highly infectious, and this high infectivity is mainly caused by the virus. Caused by the T6I and L452Q mutations, these mutations change the nature of the virus binding to the angiotensin-converting enzyme 2 (ACE2) cell receptor.
Biology Papers Archive Network pointed out that although this study has not been peer-reviewed so far, it can be determined that the Lambda variant virus infects cells as active as the Delta variant, which is currently considered to be the most infectious in the world. One of the strains.
This study pointed out that the RSYLTPGD246-253N mutation enables the variant to evade neutralizing antibodies and is described by experts as a “unique” mutation. This unique mutation is only present in Lambda, which causes widespread spread in South America. Variant virus.
The report also stated that in order to neutralize this virus variant, also known as the “Andean variant”, it is necessary to produce about 1.5 times more antibodies than other strains, because most of the genes in the N-terminal domain encode The region sequence disappears, and the antibody usually binds to the spike protein that may enter the cell at this location.
(source:internet, reference only)