Moderna: Antibody against Omicron surged 80 times after third shot with double doses!

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Moderna: Antibody against Omicron surged 80 times after third shot with double doses!

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Moderna: Antibody against Omicron surged 80 times after third shot with double doses!

Moderna’s official announcement: Antibody against Omicron surged 80 times after inoculation with the third shot of double dose!

Moderna said on Monday that in laboratory tests, the booster of its COVID-19 vaccine appears to prevent the rapidly spreading variant of Omicron.

The current version of the vaccine will continue to be Moderna’s “first line of defense against Omicron.”

The vaccine manufacturer said that the decision to focus on the current vaccine mRNA-1273 was partly due to the rapid spread of the new variant.

Moderna still plans to develop a vaccine specifically designed to prevent Omicron and hopes to enter clinical trials early next year.

Source: Global News

Dr. Paul Burton, Chief Medical Officer of Moderna, said in an interview: “The vaccine we currently have available is 1273. It is very effective and very safe. I think it will protect people through the upcoming holidays and winter, during which we will Seeing Omicron brings the most serious pressure.”

Booster neutralizing antibody increased 80 times

Moderna said that the two-dose vaccine produced low neutralizing antibodies against the Omicron variant, but the 50 microgram booster increased the neutralizing antibodies by 37 times.

For the same vaccine, if a higher booster of 100 micrograms is used, the antibody level will be higher, which is more than 80 times that of the two doses of vaccine.

In Canada, regulatory agencies have approved the use of Moderna’s vaccine as a booster, and the booster dose has been halved.

The National Advisory Committee on Immunization (NACI) recommends that vulnerable groups such as immunodeficiency can receive the third dose at the full dose.

However, Moderna and Pfizer/BioNTech’s vaccines are both associated with rare cases of cardiac inflammation, especially in young men.

Multiple studies have shown that Moderna’s vaccine may cause a higher rate of heart inflammation.

Previously, Pfizer/BioNTech provided new data on the effectiveness of its mRNA vaccine against the Omicron variant.

In a press release on December 8, the two companies stated that preliminary laboratory studies showed that three doses of Pfizer-biontech comirnity COVID-19 vaccine “neutralized the Omicron variant”, while two doses of the vaccine showed “neutralization drops”. The degree is significantly reduced”.

According to Oxford University, neutralizing antibody titer refers to the level of antibodies in the blood of an individual that can kill the virus.

The university stated that antibody levels may come from vaccination, natural infection, or a mixture of the two.

Pfizer’s data shows that compared with only two doses of vaccine, the third dose of vaccine “can increase the neutralizing antibody titer by 25 times.” The two companies said that the two doses of the vaccine may still “produce protection against re-certification.”

Pfizer/BioNTech stated that they will continue to “promote the development of Omicron variant-specific vaccines,” which is expected to be on the market in March.

Moderna: Antibody against Omicron surged 80 times after third shot with double doses!

(source:internet, reference only)

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