Drinking more coffee reduces the risk of prostate cancer in men
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Drinking more coffee reduces the risk of prostate cancer in men
BMJ Sub-Journal: drinking more coffee reduces the risk of prostate cancer in men.
A number of studies over the past few years show that more than a cup of coffee can bring many health benefits, for example, a cup of coffee with liver cancer , colon cancer and breast cancer relative risk related to low.
According to the latest forecast data released by the International Agency for Research on Cancer (IARC) of the World Health Organization , there will be an increase of 1.41 million men with prostate cancer worldwide in 2020, which has become the second highest incidence of malignant tumors in men worldwide (after lung cancer with 144 Million) .
Three-quarters of prostate cancer cases occur in developed countries in Europe and America, but since the 1970s, new cases of prostate cancer have risen sharply in Asian countries including Japan , Singapore, and China .
In 2015, the incidence of prostate cancer in Shanghai exceeded that of liver cancer for the first time, and it became the fourth highest incidence of male malignant tumors in Shanghai.
It is close to developed countries in Europe and the United States, seriously threatening the lives and health of men.
Wang Kefeng and others from Shengjing Hospital of China Medical University published in BMJ Open the title: Coffee consumption and risk of prostate cancer: a systematic review and meta-analysis ( Coffee consumption and risk of prostate cancer: a systematic review and meta-analysis ) Thesis [1] .
The study included 16 prospective cohort studies of 57,732 cases of prostate cancer and found that higher coffee consumption was significantly associated with a lower risk of prostate cancer .
This study shows that increasing coffee intake may reduce the risk of prostate cancer .
Previous studies have shown that coffee drinking is associated with reducing the relative risk of liver cancer, bowel cancer, and breast cancer , but so far, there is no conclusive evidence that coffee drinking has a potential role in reducing the risk of prostate cancer.
In order to study the association between coffee intake and prostate cancer risk, the research team searched a database of related cohort studies published as of September 2020. Eventually included 16 studies, of which seven in North America, seven in Europe, two in Japan, with a total queue more than one million men, of which 57 732 suffering from prostate cancer .
Statistical analysis showed that, with low coffee consumption (less than 2 cups a day) compared to high coffee consumption (and more than two cups a day) people and reduce the risk of prostate cancer by 9% related to drink a cup of coffee per day, prostate The risk of cancer is reduced by 1% .
Further improve the analysis of locally advanced prostate cancer and showed that with low coffee consumption (less than 2 cups a day) compared to , high coffee consumption (two cups per day and above) who localized prostate cancer risk reduction by 7%, advanced and The risk of fatal prostate cancer is reduced by 12%-16%.
Overall, as the number of coffee cups consumed daily increases, the risk of prostate cancer decreases
The research team believes that the caffeine in coffee can improve glucose metabolism, has anti-inflammatory and antioxidant effects, and can affect the level of sex hormones. These effects of coffee may affect the occurrence, development and progression of prostate cancer.
In general, this study suggests that increased coffee consumption may be related to lowering the risk of prostate cancer .
However, it is still necessary to further study to determine the underlying mechanism and the key active substances that play a role.
If it can be further proved that the association between coffee consumption and the risk of prostate cancer is causal, it may encourage men to increase coffee consumption to reduce the risk of prostate cancer.
In addition, a number of recent studies have shown that drinking coffee is related to reducing the risk of disease.
Drink more coffee to reduce the risk of chronic diseases
2020 July 23, the first of the four major medical journal ” New England Journal of Medicine ” ( NEJM ) published a report entitled: Coffee, Caffeine, and Health Review Papers [2] .
The paper pointed out that a large amount of evidence suggests that drinking coffee does not increase the risk of cardiovascular disease and cancer, and drinking 3 to 5 cups of coffee a day is associated with a reduction in the risk of several chronic diseases .
Drink more coffee to increase the survival time of patients with colorectal cancer
On September 17, 2020, the Mayo Medical Center, Dana-Farber Cancer Institute and other top international medical research institutions published the title: Association of Coffee Intake With Survival in Patients With Advanced or Metastatic Colorectal Cancer in the top medical journal JAMA Oncology . Research paper [3] .
The research team further analyzed the observation data of a large clinical trial of colorectal cancer patients and found that among the 1171 patients with metastatic colorectal cancer who received treatment, patients who drank 2-3 cups of coffee a day had a longer overall survival. The risk of deterioration is lower, and patients who drink 4 cups of coffee a day benefit more .
Drink more coffee to reduce mortality related to liver cancer
On August 14, 2020, a number of Australian research institutions collaborated and published a title in Alimentary Pharmacology and Therapeutics magazine entitled: Estimates of the global reduction in liver disease-related mortality with increased coffee consumption: an analysis of the Global Burden of Disease Dataset The paper [4] .
The paper analyzes the global burden of disease data set and shows that as coffee intake increases, liver cancer-related mortality decreases globally .
Specifically, if everyone in the world drinks at least two cups of coffee a day, the world’s The number of deaths due to liver cancer will be reduced by more than 450,000.
If everyone drinks at least four cups of coffee a day, the number of deaths due to liver cancer will be reduced by more than 720,000 .
Special reminder : This article only interprets and reports relevant research papers truthfully, and does not constitute any purchase and use advice.
Paper link:
1.https://bmjopen.bmj.com/content/11/2/e038902
2.https://www.nejm.org/doi/full/10.1056/NEJMra1816604
3.https://jamanetwork.com/journals/jamaoncology/article-abstract/2770262
4.https://onlinelibrary.wiley.com/doi/full/10.1111/apt.16020
drinking more coffee reduces the risk of prostate cancer in men
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