Drinking more coffee can reduce the risk of Alzheimer’s disease?

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Drinking more coffee can reduce the risk of Alzheimer’s disease?

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The latest research shows that drinking more coffee can reduce the risk of Alzheimer’s disease

Alzheimer’s disease (s disease of Alzheimer apos, the AD) , commonly known as ” dementia ” pathology characterized by the presence in the brain β- amyloid (A [beta]) and Tau amyloid deposition , is the most common neurodegenerative disease, patients usually Symptoms such as memory decline and weakened learning ability will appear, accompanied by emotional adjustment disorders and loss of athletic ability, which greatly affect the development of individuals, families and even society.

Currently, about 50 million people worldwide suffer from Alzheimer’s disease. As the average life expectancy of human beings increases and the aging society intensifies, the prevalence of Alzheimer’s disease is also rising.

It is estimated that by 2050, Alzheimer’s patients will increase to more than 150 million.

Recently, researchers from Edith Cowan University, Australia, in Frontiers in Aging Neuroscience journal published a study entitled: Higher Coffee Consumption Associated With Slower Cognitive Decline Is is and A [beta]-Less Cerebral Amyloid Accumulation Over 126 Months: the From the Data at The Australian Research papers on Imaging, Biomarkers, and Lifestyle Study .

This decade-long study shows that drinking more coffee may reduce the risk of Alzheimer’s disease .

Specifically, increasing coffee intake may reduce the rate of cognitive decline by slowing down the accumulation of β-amyloid (Aβ) in the brain, and alleviate Aβ-mediated oxidative stress and related neurotoxicity.

Coffee is one of the most popular beverages worldwide. 80% of adults drink at least one caffeinated beverage every day.

It is estimated that 3 billion cups of coffee are consumed every day in the world. Because it contains a large amount of caffeine, it is often consumed by people to refresh their minds and improve work efficiency.

A number of past studies have also shown that drinking coffee regularly can bring many health benefits, which are related to the reduction of the risk of liver cancer and other cancers, and the reduction of the risk of many chronic diseases.

As part of Australia’s aging, biomarker and lifestyle research, researchers at Edith Cowan University surveyed 227 elderly people with normal cognitive abilities and found out whether coffee intake affected their The rate of decline in cognitive abilities over the past decade.

The first author of the paper, Dr. Samantha Gardener , pointed out that the survey results showed that there is an association between coffee intake and several important biomarkers related to Alzheimer’s disease.

The research team found that at the beginning of the study, participants who did not have memory impairment and had a high coffee intake later changed to mild cognitive impairment (usually before Alzheimer’s disease) or developed Alzheimer’s disease. The risk is low.

Drinking more coffee has a positive effect on certain areas of cognitive function, especially executive ability, including planning, self-control, and attention. Higher coffee intake also seems to be related to slowing down the accumulation of amyloid in the brain, and the accumulation of amyloid is a key factor in the development of Alzheimer’s disease.

Dr. Samantha Gardener believes that this finding is encouraging. Although further research is needed to confirm, these data indicate that drinking coffee may be a simple way to help delay the onset of Alzheimer’s disease. People only need to do some simple habits. This may be especially useful for people who are at risk of cognitive decline but who have not yet experienced obvious symptoms.

The research team said that if you only drink one cup of coffee a day, it is recommended that you double it . Coffee made at home is usually 240g/cup. If you make two cups a day, the cognitive decline will be reduced by 8% after 18 months. At the same time, the accumulation of β-amyloid in the brain will also be reduced by 5%.

People with high coffee intake have lower accumulation of β-amyloid in the brain

The research team also pointed out that it is not yet certain how many cups of coffee a day can produce beneficial effects.

It is hoped that in the future, it will be possible to determine how much coffee to drink per day can delay the development of Alzheimer’s disease.

This study has not yet determined exactly which components of coffee have a seemingly positive effect on brain health.

Although caffeine is associated with beneficial results, the study shows that caffeine may not be the only factor in delaying Alzheimer’s disease .

“Crude caffeine” is a by-product of decaffeinated coffee and has been shown to be equally effective in preventing memory impairment in mice, while other coffee ingredients such as caffeol, kahweed alcohol and eicosanyl-5-hydroxytryptamine have also been observed To the cognitive impairment that affects animals in various studies.

Paper link:
https://www.frontiersin.org/articles/10.3389/fnagi.2021.744872/full

Drinking more coffee can reduce the risk of Alzheimer’s disease?

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