June 23, 2021

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Parkinson and Alzheimer: Coffee is proved to reduce risks

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Parkinson and Alzheimer: Coffee is proved to reduce risks

 

Parkinson and Alzheimer: Coffee is proved to reduce risks.  Coffee can reduce the risk of Parkinson’s disease and Alzheimer’s disease.

Caffeine is a central nervous system stimulant and is often regarded as a special protective agent for coffee.

In addition to refreshing, scientists have discovered that coffee has the potential to prevent and treat a variety of diseases, such as fighting dementia and reducing cancer risk.


Coffee can reduce the risk of Parkinson’s disease and Alzheimer’s disease

British “Daily Mail” pointed out that drinking 3 to 5 cups of coffee a day can help reduce the risk of Alzheimer’s disease in Nov. 2014, but no definite evidence has been found.


Alzheimer’s disease

In 1994, the outgoing President Reagan announced that he had Alzheimer’s disease. 

On October 12, 2018, Frontiers in Neuroscience published a research report. Scientists from the Krembil Institute in Canada found through research that drinking coffee may help reduce individuals suffering from Alzheimer’s disease and The risk of Jinsen disease.

Parkinson and Alzheimer: Coffee is proved to reduce risks

In the article, the researchers studied three different types of coffee, namely light roast, dark roast and decaffeinated dark roast. The researchers found that in the initial experiments, caffeine-containing and decaffeinated dark-roasted coffee had the same effect, so the protective effects of coffee observed by the researchers may not be caused by caffeine.

Subsequently, the researcher Mancini discovered a compound called phenylindanes, which appears in the roasting process of coffee beans. This compound is very special because it can effectively inhibit β amyloid and tau protein, and this The two proteins are two special protein fragments in the body of patients with Alzheimer’s disease and Parkinson’s disease, and are also the “culprits” of the disease. Therefore phenyllindane may have dual inhibitory properties.

Parkinson and Alzheimer: Coffee is proved to reduce risks

Deposit of β amyloid (red by arrow) around neurons

Phenyllindane is a natural compound, which may be one of its advantages over artificial compounds; later researchers still need to conduct more in-depth research to apply this special compound to clinical treatment.

“This is the first time anyone has studied the interaction of phenyllindane with Alzheimer’s and Parkinson’s proteins,” said researcher Dr. Mancini. For researchers, another exciting aspect of this discovery is that these coffee compounds are natural and do not need to be synthesized in the laboratory, which makes their production less complicated.

It is worth noting that due to the increased phenylindanes content caused by roasting, dark roasted coffee seems to be more protective than light roasted coffee. But the results of the study do not necessarily mean that everyone should start drinking strong coffee or roast coffee beans particularly dark. This research is still in its preliminary stages, and there are still many unknowns as to how these compounds work in the human body.

 

Little knowledge about coffee roasting

The so-called coffee roasting refers to a series of physical and chemical reactions occurring inside and outside the coffee beans by heating the green beans, and in this process the sour, bitter, sweet and other flavors of the coffee are formed to form the fullness And hue, the process of transforming raw beans into dark brown raw beans.

From the perspective of baking degree, the deeper the baking degree, the stronger the bitterness; the lighter the baking degree, the stronger the sourness.

On December 3, 2018, a new article was published in the journal PNAS. Researchers at Rutgers University in the United States discovered two compounds in coffee, EHT (Eicosanoyl-5-hydroxytryptamide) and caffeine (caffiene) , May be able to treat Parkinson.

Parkinson and Alzheimer: Coffee is proved to reduce risks

 

Caffeine is a central nervous system stimulant and is often regarded as a special protective agent for coffee. EHT is a fatty acid derivative of the neurotransmitter serotonin, found in the waxy epidermis of coffee beans. Earlier studies have shown that EHT can protect the brains of mice and prevent abnormal proteins related to Parkinson’s disease and Lewy body dementia from accumulating in the brain.

Now, the team of M. Maral Mouradian from the Rutgers Robert Wood Johnson School of Medicine has discovered that only caffeine and EHT can increase the activity of the catalyst PP2A, thereby helping to prevent the accumulation of harmful proteins in the brain.

They believe that the combination of these two compounds is expected to become a treatment option to slow down the neurological decline of the brain. M. Maral Mouradian emphasized that further research is needed to determine the protective effect of this strategy on the human brain.

However, it should be noted that these interesting studies are only collecting epidemiological evidence to prove that certain ingredients in coffee help prevent cognitive decline, but they do not mean that coffee is a treatment for neurodegenerative diseases.

Therefore, Dr. Lei Jiang from the Department of Neurosurgery of Long March Hospital reminds you that drinking coffee is safe, but it is not the “master key” to prevent disease. Excessive drinking will cause some uncertainty to your health, so it is recommended that you drink coffee in moderation.

 

The American Alzheimer’s Association recommends 10 ways to protect brain health:

1. Recognize the importance of the brain and take good care of the brain;

2. Prevent heart, blood vessel and other diseases that are directly related to the brain. Diseases such as high blood pressure, heart disease, diabetes and stroke, which greatly increase the risk of developing Alzheimer’s;

3. Understand whether your body’s condition, such as weight, blood pressure, cholesterol and blood sugar levels, are within the normal range;

4. Supplement brain nutrition, eat less fat-rich foods, and eat more foods containing vitamin C, vitamin E and other antioxidants;

5. Appropriate exercise and exercise can promote blood circulation and promote brain cell metabolism;

6. Stimulate the brain and keep the brain active, such as reading, writing, thinking, or playing games, learning, and being curious about new things;

7. Keep in touch with the society, stimulate the vitality of the brain, such as communicating with people, participating in social activities, activities that combine physical, intellectual, and social activities can best prevent the occurrence of Alzheimer’s;

8. Protect the head, and don’t let the head be damaged, such as accidental fall, etc.;

9. Avoid unhealthy habits, do not smoke, and do not drink too much;

10. Have an optimistic and positive attitude, eliminate worries and pressures, and have a forward-looking consciousness.

 

 

(source:internet, reference only)


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