U.S. animal experiments: No need to develop a booster vaccine for Omicron
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U.S. animal experiments: No need to develop a booster vaccine for Omicron
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U.S. animal experiments show that there is no need to develop a booster vaccine for Omicron.
U.S. researchers said today that monkey experiments showed that there was no significant difference in protection between the existing Moderna vaccine booster and the booster against the Omicron variant, suggesting that there may be no need to develop a booster specifically against Omicron.
Reuters reported: In this experiment, monkeys were first given two doses of Moderna’s COVID-19 (coronavirus disease 2019) vaccine. After 9 months, a third dose of traditional Moderna or a booster shot specifically for Omicron was administered.
The researchers then tested various aspects of the monkeys’ immune responses and exposed them to the virus. The study found that the two boosters produced “comparably and significantly increased neutralizing antibody responses” against all variants of high concern (VOC), including the Omicron variant.
Both Moderna and Pfizer/BioNTech have begun human clinical trials of the Omicron booster.
“This is very, very good news,” study co-author Daniel Douek, a vaccine researcher at the National Institutes of Allergy and Infectious Diseases (NIAID), said in a telephone interview. It becomes the Omicron-specific vaccine.”
Duke believes that both the original vaccine and the Omicron-specific vaccine have a “cross-reactive” effect and can recognize many different variants, so they can play this role.
Dr. John Moore, a professor at Weill Cornell Medical College who was not involved in the study, said the results were consistent with tests of the Beta variant of the Moderna booster. The results were similar.
“The monkey data is usually very predictive, but the human data has to be looked at,” he said.
U.S. animal experiments show that there is no need to develop a booster vaccine for Omicron.
(source:internet, reference only)
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