October 2, 2022

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mRNA is expected to treat heart diseases by mRNA vaccine technology

mRNA is expected to treat heart diseases by mRNA vaccine technology



 

mRNA is expected to treat heart diseases by mRNA vaccine technology.


Using the exact same technology used in the Pfizer and Moderna vaccines, the researchers injected microRNAs into the heart, prompting the surviving heart cells to proliferate. This revolutionary approach has been successfully used to regenerate damaged pig hearts. 


Researchers are using the same technology used in the coronavirus vaccine to repair damaged hearts to create the world’s first drug to cure heart disease patients.

 

 

 

“Reference News” published a report on the British “Times” website on Tuesday (April 19) titled “Coronavirus vaccine technology may bring the first drug to cure heart disease”.

 

According to reports, scientists at King’s College London have discovered the key genetic code – messenger ribonucleic acid (mRNA), which produces proteins that promote the generation of healthy new heart cells. Using the same technology used in Pfizer’s and Moderna’s vaccines, this messenger RNA can be delivered directly to the heart muscle after a heart attack.

 

About 100,000 people in the UK are admitted to hospital for a heart attack each year. Heart disease occurs when blood flow to the heart is blocked, causing many heart cells to die. Because the human heart does not have the ability to repair itself, patients are left with permanent scars, which often lead to heart failure.

 

So far, the revolutionary approach has been successfully used to regenerate damaged pig hearts, and human trials will begin within two years.

 

Professor Mauro Jacca, who led the research, said: “We have a fixed number of muscle cells in the heart from birth and these cells remain the same when we die. The heart does not have itself after a heart attack. Repair capacity. Our goal is to find a treatment that allows the surviving cells to proliferate.”

 

He said: “We use the exact same technology as the Pfizer and Moderna vaccines to inject microRNAs into the heart, which causes the surviving heart cells to proliferate. The new cells will replace the dead cells, and instead of scarring, the patient will develop a New muscle tissue is created.”

 

Jaka’s team at the Heart Foundation Centre of Excellence at King’s College London is also developing a therapy to prevent cells from dying during a heart attack. “We’ve discovered three proteins that prompt heart cells to repair themselves, preventing them from dying,” Jaka said. “The idea is to make these proteins so that after a patient has a heart attack – in an ambulance Or when the patient arrives at the hospital – give them an injection of these proteins right away.”

 

“If the clinical trials go well, this will be a blockbuster drug in the history of cardiology,” Jaka said. “Both approaches are very exciting. This will be truly transformative. It will be a whole new field.”

 

 

 

mRNA is expected to treat heart diseases by mRNA vaccine technology

(source:internet, reference only)


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