What are Stem Cell Reinfusion and related issues?
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What are Stem Cell Reinfusion and related issues?
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What are Stem Cell Reinfusion and related issues?
Everything you need to know about stem cell reinfusion is here!
With the development of medical technology, stem cell therapy has become the most promising drug candidate and has become an important direction of research and development in many countries.
Stem cell therapy is the use of in vitro isolation, culture, and directional induction of differentiation of stem cells to cultivate a new, normal, younger cell, tissue, organ, etc.
Today we mainly come to understand the following, what should we pay attention to before and after stem cell infusion!
What is Stem Cell Reinfusion?
Stem cell reinfusion also refers to “stem cell transplantation”, which is a part of cell biological therapy.
It mainly obtains the stem cells needed for clinical application after identifying, separating and purifying cells from various human tissues in vitro;
and then through intravenous injection or intervention By reinfusion intervention, stem cells move to the damaged organs and tissues to promote cell repair, regeneration and renewal.
At the same time, it activates the body’s own “self-healing function”, and uses stem cells with the ability to self-replicate and differentiate to repair damaged cells or tissues in the body to achieve the purpose of rebuilding the body’s functions.
What kind of work do the stem cells reinfused into the human body do?
Activation of dormant cells:
dormant cells are cells that have lost their cell functions.Stem cells can directly activate dormant cells to restore their original physiological functions.
Replacement of necrotic cells:
Stem cell homing can replenish and replace necrotic cells in time, thereby maintaining the normal function of the body and delaying aging.
Repair damaged cells:
Unfavorable factors in the external environment will cause cell damage during cell metabolism. Stem cells can repair damaged cells and prevent cell disease.
Regenerative active cells:
Stem cells have multiple differentiation potentials, which can increase the number of functional cells, enhance cell activity, and achieve the purpose of anti-aging.
Who is suitable for stem cell therapy?
Pursue young and energetic people;
Three highs (high blood fat, high blood pressure, high blood sugar);
immune system disorders;
Sub-health, high work pressure, irregular life;
Cardiovascular, liver dysfunction, endocrine dysfunction, bone degeneration and other aging population.
Who are the contraindications for stem cell therapy?
AIDS, active hepatitis B, syphilis positive; highly allergic constitution or history of severe allergies;
Malignant tumors are undergoing radiotherapy and chemotherapy treatment; it is contraindicated during the treatment period for sudden diseases, and it can be used for 2-3 months when the condition is stable;
coagulation disorders; mental illness; pregnant women;
Systemic infection or severe local infection.
Note: Stem cell infusion must go through strict physical examination and expert evaluation before proceeding
Precautions the day before stem cell reinfusion
Focus on a light, easy-to-digest diet, and avoid spicy and irritating seafood. Avoid strenuous exercise, go to bed early at night and get enough sleep.
Precautions after stem cell reinfusion
Try not to stay up late, do not do strenuous exercise within three days after treatment, do not go to the sauna within one week after treatment, avoid strong sunlight, sauna baths, and mineral salt baths within one month after treatment, and avoid X-ray examinations within two months ( except for special health problems).
The infusion of stem cells is the same as the usual infusion, only there is slight pain during the puncture, and the pain is tolerable.
During the infusion process, due to individual differences, there may be transient fever and allergic reactions, but they are all mild and will be relieved the next day.
How long does it take for stem cells to work? How long does it last?
First of all, each person’s application is different, some are sub-healthy (different symptoms), some are diseases (different types of diseases), which involve gender, age, region, genetics, single disease and multiple diseases Factors such as , disease progression, etc., cause the differences between individuals to vary widely.
Secondly, the infusion methods are different, and there will be differences in reinfusion reactions such as arterial, intravenous, local injection, and whether it is combined with other therapies;
Thirdly , lifestyle and work and rest habits will also have an impact on the survival rate and activity of cells entering the body. Therefore, we must maintain good living habits and work and rest time in daily life, go to bed early and get up early, and keep exercising.
Finally, factors such as the cell type used, the number of cells, the interval period, etc. will also lead to different final results.
All in all, every point we may think of will eventually affect the effect of cells and the problem of sustainability.
At present, the more common rule is that there will be a relatively obvious injection reaction in a few minutes to 3 days, and the cells will migrate to produce a biological response in the next two weeks, and the curative effect will gradually occur in the next 6-12 weeks, and the duration will be one year to several years. Years vary.
How long can stem cells survive in the body?
Mesenchymal stem cells mainly play the role of immune regulation and cytokine secretion in vivo.
Then we think it doesn’t need to survive in the body for a long time, and it’s best to be slowly rejected after finishing the work!
Judging from the current research results, whether it is local injection or systemic injection, whether it is autologous stem cells or allogeneic stem cells, the body will gradually clear stem cells, and the speed of removal is related to many factors, including the body’s immune system, input pathways, and source of cells .
The age of the tissue, cell donor, and the length of time the cells were cultured in vitro, etc.
Are there any side effects of stem cell reinfusion?
During the process of preclinical animal experiments and clinical experiments of stem cells, side effects such as various toxic reactions, genetic influences, local stimulation, and immune reactions are strictly inspected.
It cannot be guaranteed that stem cells have no side effects at all, but researchers will conduct a comprehensive evaluation of the benefits of efficacy and the risk of side effects to evaluate whether stem cells can be used for this indication.
The general principle is that when stem cells are used in the field of non-serious diseases, such as for beauty, sports injury repair, etc., the requirements for side effects of stem cells will be very strict, and generally no side effects can be allowed to be used.
When using stem cells in serious and fatal diseases, considering the risk-benefit comparison, some minor side effects are unavoidable, but overall the patients definitely benefit.
What are the common manifestations after stem cell reinfusion?
1. Feeling excited and better;
2. Feeling tired with a little drowsiness;
3. No feeling at all, very stable;
4. Fever occurs, usually within 24 hours to about 38 ℃, and returns to normal within 3 days (maybe) Just prepare ibuprofen);
5. Slight muscle soreness may occur.
According to the data analysis, more people feel tired, because the repair and activation work in the body is going on intensely , just like people with viral flu feel tired because the immune system in the body is being mobilized to fight against the invading virus, Bacteria fight wars, so feeling tired is a normal repair response
What are Stem Cell Reinfusion and related issues?
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