Daily Sugary Drink Consumption Linked to Increased Liver Cancer and Disease Risk

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Daily Sugary Drink Consumption Linked to Increased Liver Cancer and Disease Risk

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Daily Sugary Drink Consumption Linked to Increased Liver Cancer and Disease Risk.

Research Finds Daily Consumption of Sugary Drinks Increases the Risk of Liver Cancer and Chronic Liver Disease.

A team of researchers from Brigham and Women’s Hospital, a founding member of the Massachusetts General Brigham health system, led an initial study aimed at exploring the relationship between the consumption of sugary and artificially sweetened beverages and the incidence of liver cancer and chronic liver diseases. The study’s findings were recently published in the “JAMA” journal.

Approximately 65% of American adults regularly consume sugary drinks. Chronic liver disease is a major contributor to global diseases and deaths, potentially leading to liver cancer and liver disease-related mortality. The research discovered that postmenopausal women who consume sugary drinks daily have a significantly higher risk of these liver-related outcomes compared to women who drink fewer beverages.

“As far as we know, this is the first study reporting an association between the intake of sugary drinks and the mortality rate from chronic liver disease,” said Dr. Longgang Zhao, the first author and a postdoctoral researcher at the Channing Division of Network Medicine at Brigham and Women’s Hospital, who worked alongside senior author Dr. Xuehong Zhang (MBBS, ScD). “If our findings are confirmed, they may provide a basis for public health strategies aimed at reducing liver disease risk based on data from large, geographically diverse cohorts.”

This observational study included nearly 100,000 postmenopausal women from the Nurses’ Health Study, a large prospective women’s health initiative. Participants reported their consumption of soft drinks and fruit drinks (excluding 100% fruit juice) at baseline and reported their consumption of artificially sweetened beverages three years later. The median follow-up time for participants exceeded 20 years. Researchers examined self-reported rates of liver cancer incidence and deaths resulting from chronic liver diseases such as fibrosis, cirrhosis, or chronic hepatitis, further verified through medical records or the National Death Index.

In the final analysis, a total of 98,786 postmenopausal women were included. Compared to women who consumed fewer than three sugary drinks per month, women who consumed one or more sugary drinks per day had an 85% higher risk of developing liver cancer and a 68% higher risk of dying from chronic liver disease.

The authors noted that this study is observational in nature and cannot establish causation, relying solely on self-reported information regarding intake, sugar content, and outcomes. Further research is needed to validate this risk association and determine why sugary drinks appear to increase the risk of liver cancer and other diseases. Additionally, more research is required to elucidate potential mechanisms by integrating genetics, preclinical and experimental research, and omics data.

Daily Sugary Drink Consumption Linked to Increased Liver Cancer and Disease Risk

(source:internet, reference only)

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