COVID-19 vaccine may not be effective for obese people

COVID-19 vaccine may not be effective for obese people

COVID-19 vaccine may not be effective for obese people. Control your weight and lay a solid foundation for subsequent vaccination. The coronavirus pneumonia (COVID-19) epidemic is still raging around the world, and new mutant virus strains have been confirmed one after another. The world is speeding up the development and vaccination of vaccines. Recently, an internationally renowned journal Nature issued an article to remind the public: If overweight or obesity is possible As a result, the effectiveness of vaccination is reduced or even ineffective.

At present, COVID-19 is a new global infectious disease, and the high risk of death of severely ill patients has attracted much attention. Some researchers have suggested that obesity may be one of the risk factors for the aggravation of COVID-19.

Patients with BMI≥35kg/m2 have a 74% increased risk of being transferred to the ICU. Among COVID-19 patients, the risk of death for obese people has increased by 48%.

Therefore, the probability of obese people suffering from COVID-19 is higher than that of others, and compared with other patients, obese people are more likely to be infected with COVID-19 and have a higher probability of worsening and worse prognosis. The reason is that obese people are in a persistent chronic inflammatory state, which makes the body unable to attract immune cells to resist viral infection, even if the incidence rate after vaccination is higher than that of normal people. Obesity can damage the function of the body’s B cells, so it is likely to reduce the effectiveness of the vaccine, that is, a stronger vaccine may be required.

In fact, studies have long found that common vaccines such as influenza, hepatitis B, tetanus and rabies are generally less effective in obese people than the general population. For example, if overweight/obese people receive hepatitis B vaccine, their antibody levels will drop significantly after 11 months, but normal people do not. Compared with adults of normal weight, obese adults are twice as likely to get influenza after vaccination.

Although there is no sufficient evidence that overweight/obesity will reduce the effectiveness of the COVID-19 vaccine, there is no reason to believe that the new coronavirus pneumonia vaccine will be different from other vaccines. Obesity is a serious global problem, and the poor vaccine response observed in obese people cannot be ignored. In view of the increasing number of obese people and their susceptibility to COVID-19, when developing and preparing vaccines, the relevant immune response of such people must be taken into account to ensure that the new coronavirus vaccine is also effective for obese people.

The real problem is that overweight/obesity cannot be solved in a short period of time, and scientists have not had the energy to develop targeted vaccines for overweight/obese patients, and widespread vaccination of vaccines is imperative. For the health of yourself and your family and friends, you should Speed ​​up weight control through lifestyle adjustments, and lay a solid foundation for subsequent vaccination.

(source:internet, reference only)

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