- Targeting Sugar Molecules in Sugar-Immune Therapy
- Monkeypox Initial Infection Provides Protection Against Secondary Infection
- What is Genetic Toxicity of Base Editing and Prime Editing?
- What is the Scientific Foundation of mRNA Technology?
- This amino acid can significantly alleviate post-COVID-19 sequelae!
- What are Challenges in CAR-T Cell Therapy for Cancer treatment?
The fatty liver will bring the higher risk of stroke!
The fatty liver will bring the higher risk of stroke! The study found that compared with the general population, patients with non-alcoholic fatty liver disease (commonly known as fatty liver, NAFLD) appeared The risk of stroke and myocardial infarction is significantly increased, and the more serious the fatty liver, the higher the risk.
The study included nearly 80,000 participants who had no history of stroke, cancer or myocardial infarction in Kailuan, Tangshan, Hebei. During an average follow-up period of 10.34 years, 3490 strokes were recorded. After excluding alcoholism and other liver diseases, ultrasound examination found that 24874 (31.18%) participants had fatty liver. Mild, moderate and severe fatty liver accounted for 20.26%, 8.94% and 1.93% respectively. After adjusting for confounding variables, it was found that compared with participants without NAFLD at baseline, the risk of ischemic stroke in NAFLD patients increased by 16% (95% CI: 1.07 to 1.26). The risk of stroke in patients with mild, moderate, and severe NAFLD was 1.15 times (95% CI 1.05–1.25), 1.19 times (95% CI 1.06-1.34), and 1.21 times (95% CI 1.08-1.50), respectively ).
With the rapid increase in obesity and diabetes, NAFLD is affecting 25-30% of adults in some countries. Warnings such as “mild fatty liver” also appear on people’s physical examination reports, but they are often regarded as “unimportant” and are not taken seriously. “Fatty liver” seems unremarkable, but the appearance of fatty liver means that excess fat outside the body is deposited in places where it should not appear (such as the liver, heart, and pancreas), and the liver and systemic inflammation cascades are activated. There may be increased oxidative stress, adipocytokines disorder, and hypercoagulable state, which will greatly increase the risk of stroke.
In recent years, the global incidence of NAFLD has been rising with the increase of obesity and diabetes, it is very important to improve people’s awareness of fatty liver and timely intervention. In addition to screening for diabetes in the clinic, it is also important to conduct cardiovascular and cerebrovascular risk assessment for patients diagnosed with NAFLD. In actual treatment, not only should conduct behavioral and lifestyle guidance, and strive to reduce liver fat, but also consider the benefits of weight loss on the risk factors of acute myocardial infarction and stroke, including the improvement of blood lipids, blood sugar, and blood pressure.
(sourcechinanet, reference only)