April 2, 2023

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What is the “fatty liver” that cannot be ignored?

 

What is the “fatty liver” that cannot be ignored?  The liver is responsible for decomposing drugs. Certain drugs or chemical poisons such as tetracycline, adrenocortical hormone, puromycin, cyclohexamine, imitrine, and arsenic, lead, silver, mercury, etc. can also harm the liver.

A 20-year-old man, who was 173cm tall and weighed more than 180 kilograms, came to the fatty liver clinic. He had a b-ultrasound examination of severe fatty liver and high liver function transaminase. Obviously, this patient is obviously obese and has abnormal liver function. The current abnormal liver function is what we call steatohepatitis.

 

When it comes to fatty liver, everyone is not unfamiliar. With the change of lifestyle, the aging of the population and the increase in obesity, drinking, etc., the prevalence of fatty liver disease has soared up to 30%, and the affected population has exceeded 200 million. Fatty liver disease has replaced hepatitis B as the largest liver disease in some countries.

 

Twenty-five percent of adults worldwide suffer from fatty liver, and the incidence rate in some parts of China reaches 45%. Moreover, during the New Year holidays, “household eating and drinking for a while” causes fatty liver to be very common.

Many people have different degrees of fatty liver in their physical examinations, because fatty liver generally has no obvious clinical symptoms, so many people don’t treat it as the same thing, and some of them will eventually develop into Liver cirrhosis, liver cancer.

 

1. What is fatty liver?

Fatty liver, the full name is “fatty liver disease”, refers to the pathological changes caused by excessive accumulation of fat in liver cells due to various reasons. It is a common pathological change of the liver, rather than an independent disease. The fat content of the liver of healthy people accounts for about 5% of the liver weight. When the liver fat weight exceeds 5% of the liver weight, it is fatty liver, more than 15% is moderate fatty liver, and more than 30% is severe fatty liver.

Although fatty liver is a reversible disease, if fatty liver affects liver function and is not treated in time, simple fatty liver will develop into hepatitis, which will continue for a long time, and liver fibrosis will appear. This kind of fibrous deposition is increasing, and it may develop into liver cirrhosis or even liver cancer.

 

2. Who is prone to fatty liver?

Fat people

Obesity is the main cause of fatty liver. When there are too many lipids, the apolipoprotein in the liver is not enough to bind all the fat, and the remaining fat is deposited in the liver cells to form an obese fatty liver. The degree of accumulation of fat in the liver is positively correlated with body weight, so the fatter the liver, the more likely it is to develop fatty liver.

Drinker

People who drink for a long time are prone to alcoholic fatty liver, and their livers have fatty infiltration. According to statistical analysis, people who drink more than 80 to 160 grams of alcohol per day have a 5 to 25-fold increase in the incidence of alcoholic fatty liver.

Diabetic

Fatty liver is not only related to the degree of obesity, but also related to eating fatty foods or excessive sugary foods. Statistics show that about 58% of diabetic patients can develop fatty liver, especially obese adults.

Malnourished people

When insufficient food intake, digestive disorders, etc. cause malnutrition, the body’s protein is lacking, and the liver cannot incorporate apolipoprotein (a tool for transporting fat), which is easy to accumulate fat in the liver.

People who lose weight fast

Insufficient intake of protein and excessive intake of carbohydrates cause liver protein synthesis disorders and cause nutritional deficiency fatty liver. This is because under normal circumstances there will always be some fat in the liver, which has to be transported out of the liver through a protein (apolipoprotein). If you are malnourished and there is a serious lack of protein in the body, the protein responsible for transporting fat in the liver will be significantly reduced, which will cause fat to accumulate in the liver, so fatty liver will also occur.

Drug factors

The liver is responsible for decomposing drugs. Certain drugs or chemical poisons such as tetracycline, adrenocortical hormone, puromycin, cyclohexamine, imitrine, and arsenic, lead, silver, mercury, etc. can also harm the liver. It should be noted that lipid-lowering drugs can also interfere with lipoprotein metabolism, and long-term abuse will also increase the chance of drug-induced fatty liver formation.

 

 

3. What are the symptoms of fatty liver?

1. Symptoms of mild fatty liver Most mild patients have no clinical symptoms, some patients with fatty liver occasionally feel fatigue, and some patients with fatty liver have a feeling of fullness in the right upper abdomen. The vast majority of fatty liver is diagnosed by physical examination.

2. Symptoms of patients with moderate to severe fatty liver The majority of patients with moderate to severe disease will have some typical clinical symptoms, including fatigue, indigestion, nausea, anorexia, abdominal distension, swelling of the liver area, or even pain, loose stools, unshaped stools, and stools The number of times and so on.

 

(source:internet, reference only)


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