May 30, 2024

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How to treat reflux esophagitis?

How to treat reflux esophagitis?


How to treat reflux esophagitis?   Reflux esophagitis is a common disease in gastroenterology. Although this disease is not serious, it also affects the quality of life and is easy to recur. Why can’t it be treated thoroughly over and over again? How should reflux esophagitis be treated? Let’s talk about the treatment of reflux esophagitis today, don’t treat it blindly!

How to treat reflux esophagitis?



What is reflux esophagitis?

Reflux esophagitis (Reflux esophagitis, RE) is a type of gastroesophageal reflux disease, which refers to the damage of the esophageal mucosa caused by acid (base) reflux. In patients with reflux esophagitis, different degrees of inflammation can be found in the esophagus under endoscopy. Stomach contents reflux to the esophagus, with heartburn, acid reflux, chest pain, epigastric pain, epigastric burning sensation, belching, etc. as the main symptoms, and the complications are mostly otolaryngology and chronic respiratory diseases.


The classification is mainly based on the situation of the esophageal mucosa under endoscopy, which represents the different severity of the disease. The following is the classification basis:

Normal: The mucosa is normal without damage (may be accompanied by histological changes);

Grade A: There are 1 or more spots or strips of redness and erosion in the mucosa, but the long diameter is less than 5mm;

Grade B: There are 1 or more spots or strips of redness and erosion in the mucosa, with a long diameter> 5mm, but no fusion lesions; Grade C: There are strips of redness, erosion, and fusion in the mucosa, but Has not progressed to full circumference, fusion circumference <75%;

Grade D: Mucosal lesions are extensive, redness, erosion and fusion cover the whole circumference, and the fusion circumference is ≥75%.


How to prevent reflux esophagitis?

The occurrence of reflux esophagitis is related to daily eating habits and living habits, so try to prevent the predisposing factors of this disease.

Overeating is strictly prohibited, eating within 2 hours before going to bed, and not lying down immediately after eating;

Eat more digestible foods and avoid spicy foods;

People with obesity, due to high intra-abdominal pressure, will cause gastric acid reflux to the esophagus, thereby triggering RE;

People with long-term high stress, depression and anxiety are also prone to induce RE.

How to treat reflux esophagitis

The purpose of treatment of reflux esophagitis is to quickly relieve symptoms, cure the disease, reduce recurrence, prevent complications, and improve the quality of life of patients. At the same time of treating the cause of the disease, attention should also be paid to general treatment such as diet and rest. If necessary, consider endoscopic treatment and surgical treatment.


Medical treatement

Acid inhibitors are divided into three categories: H2 receptor blockers, proton pump inhibitors (PPI), potassium ion competitive acid blockers (P-CBA).

At present, conventional acid suppressing drugs are proton pump inhibitors, which can relieve reflux symptoms quickly, but they also have many disadvantages:

1. The onset is slow, and it needs to be taken continuously for 3-5 days to achieve the required acid suppression effect;

2. Short half-life, unable to suppress acid for a long time, and poor control of night acid;

3. To eat twice a day may be effective. It needs to be taken before meals, otherwise it cannot disintegrate in the body;

4. Two-thirds of patients will experience recurrence of symptoms after stopping the drug.


Potassium ion-competitive acid blocker (P-CAB) is the latest class of drugs. It uses a new mechanism of action to solve the above problems. The first time the drug is taken, the effect can be almost maximized, and the effect is long-lasting, so the esophageal mucosa The repair is faster (recommended course of treatment is 4 weeks), the healing rate of severe esophageal injuries is higher, and there is less recurrence. The effect is not affected by food, and people with fast metabolism of prazoles are also effective. Although the current price of this type of medicine is a bit more expensive than that of prazole, the shorter course of treatment and less recurrence rate make its treatment cost more economical, and its safety is similar to that of prazole, which can be described as a new generation of “how fast An acid suppressant that saves money.


Finally, it is emphasized that if you often have acid reflux, heartburn, or even affect sleep; or chronic asthma or chronic cough that does not heal for a long time, you need to be alert to the symptoms of reflux esophagitis and seek medical attention in time to avoid aggravation.

(source:internet, reference only)

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