May 19, 2024

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Omeprazole: Only needed in these 3 conditions

Omeprazole: Only needed in these 3 conditions


Omeprazole: Only needed in these 3 conditions.  Omeprazole is a good medicine, but it is only needed in these 3 conditions. Don’t take it randomly.

Omeprazole: Only needed in these 3 conditions

As a classic stomach medicine, omeprazole is a household name and everyone knows it, and it can be described as the “magic medicine” of digestive science!

But the greater the reputation, the more trouble. The biggest trouble of omeprazole and its similar drugs is being abused. In many cases, as long as the stomach is not good, omeprazole is used to eat, and even the stomach is good. Eat too, it’s called the prevention of stomach problems!

Therefore, it is necessary to correct this abuse phenomenon and analyze which conditions really need to take omeprazole. At the same time, it is recommended not to take omeprazole at will. This is risky. It is best to consult a professional and only if necessary. eat.


3 situations where omeprazole can be taken

As a proton pump inhibitor, Omeprazole selectively inhibits the H+-K+-ATPase (proton pump) of gastric parietal cells, thereby preventing various stimulating factors (histamine, food, acetylcholine, and pentagastrin). Etc.) The secretion of gastric acid caused by it can produce a powerful inhibitory effect. To put it simply, omeprazole is a powerful gastric acid inhibitor.

So when does omeprazole need to be used? According to the instructions, omeprazole is suitable for gastric ulcer, duodenal ulcer, stress ulcer, reflux esophagitis, and Zollinger-Eddle syndrome (gastrinoma), etc. The specific conditions can be summarized into 3 situations. The introduction is as follows.


1) There is a clear gastric mucosal damage: usually gastroscopy is used to check the gastric mucosa with ulcers, erosions, congestion, edema, etc. At this time, omeprazole injection is often needed, which is more effective and faster to inhibit gastric acid.

2) There is obvious acid reflux or heartburn: such as reflux esophagitis is caused by acid reflux; there is obvious abdominal pain and heartburn. Note that mild acid reflux, heartburn, and abdominal pain may be transient. With a little attention, you can often get better on your own without taking omeprazole.

3) Prevent severe diseases (such as cerebral hemorrhage, severe trauma, etc.) from stress conditions and upper gastrointestinal bleeding caused by gastric surgery.


Precautions for taking omeprazole

Taking omeprazole, in addition to paying attention to the above indications, it is also necessary to pay attention to the use of omeprazole in patients with severe renal insufficiency and infants and young children. Patients with severe liver insufficiency should use omeprazole with caution, and halve the dose of omeprazole if necessary. Pregnant and lactating women do not use it as much as possible. There is no need to adjust the dose of omeprazole in the elderly. Omeprazole enteric-coated tablets should be swallowed whole, and at least half a cup of liquid (≥50ml) should be used when taking it. The tablets should not be chewed or crushed. They can be dispersed in water or slightly acidic liquids (such as juice), and the dispersion must be taken within 30 minutes.

In addition, generally, omeprazole does not need to be taken for a long time, and the drug can be stopped when symptoms improve, such as gastric ulcer, and the drug can be stopped within 10 to 14 days. Of course, the two diseases of gastroesophageal reflux disease and gastrinoma are exceptions, which require long-term omeprazole.



In short, only the above three conditions need to take omeprazole. Other conditions are off-label medications. Be cautious. Of course, ordinary people often cannot judge. It is best to decide whether to take medication under the guidance of a gastroenterologist. If necessary, take it. The dosage and time also need to be clarified. It is worth noting that in the process of oral omeprazole, attention should be paid to the manufacturer of the omeprazole taken. There are some differences in the indications of omeprazole produced by different manufacturers. In order to avoid the occurrence of off-label use of drugs, physicians should pay attention to the manufacturer and instructions of omeprazole before prescribing a prescription, and cannot be generalized.


(source:internet, reference only)

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