August 17, 2022

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Too much BCAA in dinner food may affect cardiovascular health

Too much BCAA in dinner food may affect cardiovascular health

Too much BCAA in dinner food may affect cardiovascular health.  Too much food rich in BCAA during dinner may have a negative impact on the body’s cardiovascular health.

Dinner can be said to be the most time-consuming and the easiest to eat more and more miscellaneous meals. With the faster pace of modern life, poor office workers have time to meet up with friends for a drink, or make some food that they love, and enjoy dinner. However, there are many precautions for eating dinner. If a taboo is violated, it will cause health problems.

Recently, researchers from the University of Alabama at Birmingham published an article titled Branched chain amino acids selectively promote cardiac growth at the end of the awake period in the Journal of Molecular and Cellular Cardiology. The study found that eating in the evening Too much food rich in branched chain amino acids (BCAA) may have a negative impact on the body’s cardiovascular health.

In order to verify the negative effects of BCAA, first, the researchers constructed a C57BL6/J mouse model, provided the mice with diets with different BCAA content daily for 4 weeks, and then monitored the mice’s cardiac parameters. Studies have found that consuming BCAA during dinner can cause a sharp increase in the heart, thereby increasing the size of myocardial cells by 75% within 4 hours. Not only that, excessive consumption of BCAA can worsen heart disease.

As we all know, BCAA promotes protein synthesis, and this mechanism of action is achieved by activating the mTOR signal transduction axis. Therefore, researchers speculate whether the heart selectively enhances BCAA-induced mTOR signaling in the evening?

Subsequently, the researchers used the protein synthesis inhibitor “rapamycin” to further verify this conjecture and found that BCAA can increase the phosphorylation status of five mTOR signal transduction components, which further shows that eating dietary BCAA can cause cardiac hypertrophy.

Not only that, the researchers also found that the BCAA diet in the evening not only induces cardiac hypertrophy, but also worsens the remodeling of the heart, leading to a sharp decline in the systolic function of the heart, and ultimately leading to heart failure.

All in all, this research has positive significance for the development of human health. It can bring a warning effect to people suffering from obesity, diabetes, heart disease and other chronic diseases. Eat more protein-rich foods for breakfast and eat less foods that are rich for dinner. Protein foods, especially red meat, poultry, eggs, nuts and other foods with high BCAA content

(source:internet, reference only)


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