December 8, 2021

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Rutgers University: Detect stress hormones from a drop of blood

Rutgers University: Detect stress hormones from a drop of blood

 

 

Rutgers University: Detect stress hormones from a drop of blood.  A research team led by Rutgers University has developed a microchip that can measure stress hormones in real time from a drop of blood.

 


Rutgers University: Detect stress hormones from a drop of blood

Image: Description of electron detection of pressure molecules in blood in nanopores.

 

A research team led by Rutgers University has developed a microchip that can measure stress hormones in real time from a drop of blood.  The research was published in the journal “Science Advances”.

Cortisol and other stress hormones regulate many aspects of our physical and mental health, including sleep quality. High levels of cortisol can lead to poor sleep quality, which increases stress, leading to panic attacks, heart attacks, and other diseases.

Currently, measuring cortisol requires expensive and cumbersome laboratory settings, so the team led by Rutgers University is looking for a way to monitor its natural fluctuations in daily life and provide feedback to patients so that they can be at the right time Receive the right treatment.

The researchers used the same technology used to make computer chips to create sensors that are thinner than human hair and can detect biomolecules at a lower level. They verified the performance of the miniaturized device on blood samples from 65 patients with rheumatoid arthritis.

“The use of nanosensors allows us to directly detect cortisol molecules without any other molecules or particles as labels,” said Reza Mahmodi, the first author of the study, who is a director of Rutgers University, New Brunswick. Postdoctoral scholar in the Department of Computer Engineering.

Mehdi Javanmard, an associate professor and senior author in the Department of Electronic and Computer Engineering at Rutgers University, said that with technologies like the team’s new microchip, patients can monitor their hormone levels and better manage chronic inflammation, stress, and chronic inflammation at a lower cost. Other conditions.

He added: “Our new sensor produces an accurate and reliable response. It can continuously read cortisol levels for real-time analysis.” “It is very useful in the non-invasive cortisol measurement of other fluids (such as saliva and urine). Great potential.” The fact that molecular tags are not required eliminates the need for large and bulky instruments such as optical microscopes and plate readers, so that the reading instrument can finally be measured in a small pocket-sized box, and even one day can be installed on the wrist. Bring it. “

 

(source:internet, reference only)


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