Ivermectin is magic drug for COVID-19 or abused of veterinary drugs?
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Ivermectin is magic drug for COVID-19 or abused of veterinary drugs?
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Ivermectin is magic drug for COVID-19 or abused of veterinary drugs?? What exactly is Ivermectin?
Recently, the claim that the United States and India have discovered the “magic drug” for the treatment of COVID-19 pneumonia has begun to spread. There are even some media reports that thanks to Ivermectin, Uttar Pradesh, India COVID-19 cases are cleared.
In fact, last year there was already news about relying on “ivermectin” to treat COVID-19 pneumonia, and some patients even used ivermectin for deworming livestock.
However, Ivermectin has been pointed out that it has not been proven to be effective in the treatment of COVID-19 pneumonia, and there are suspected poisonings in patients who have used the drug. On October 21, the World Health Organization reiterated in a message on its official website: Except for clinical trials, it is not recommended to use ivermectin for COVID-19 pneumonia.
Source: WHO official websiteSource: WHO official website
What kind of medicine is Ivermectin? Looking for drugs for the treatment of COVID-19 pneumonia, why do researchers turn their attention to ivermectin? So far, what effect does it have on the new coronavirus?
Ivermectin against river blindness
Ivermectin is a broad-spectrum antiparasitic drug that has been discovered by humans for almost 50 years.
In the 1970s, Japanese scientist Tomo Omura discovered a new type of Streptomyces from the soil; subsequently, a company extracted the antibiotic avermectin from soil samples; it was transformed by William C. Campbell, ivermectin Born. Tomo Omura and William C. Campbell are two scientists who won the Nobel Prize in Physiology or Medicine in the same year as Chinese scientist Tu Youyou in 2015.
Ivermectin was launched in 1981 and was first used in the animal husbandry field. After 1987, it was discovered to be able to treat onchocerciasis and to treat human diseases.
Onchocerciasis, also known as river blindness, is caused by the parasite Onchocerciasis. It is transmitted to humans through repeated bites of infected black flies, which can cause severe itching, skin damage, visual impairment, and even permanent blindness.
According to the introduction of the World Health Organization, the core strategy for the elimination of onchocerciasis in Africa is to treat with ivermectin under the guidance of the community; the practice in the Americas is to treat with ivermectin on a large scale twice a year.
At present, ivermectin is still an anti-intestinal parasite drug that can be used by both humans and animals, but it is rarely used by humans.
In some areas where parasitic diseases are still relatively common, Ivermectin may be used more. In most areas, such as cities and other places where parasite control is better, ivermectin has been used less frequently.
Can Ivermectin cure the COVID-19 now?
In the effort to resist the new coronavirus, people once again set their sights on the “old medicine” ivermectin.
In addition to the research and development of special-effect drugs, some researchers have tried to “use old drugs in new applications.” For example, in April 2020, an Australian research team published an article stating that ivermectin can inhibit the replication and growth of the new coronavirus within 48 hours. However, this is an in vitro experiment with a single high-dose administration in a laboratory environment.
Overall, there is no definitive evidence, or there is no reliable evidence that ivermectin is effective in the treatment of COVID-19 pneumonia.
What does an in vitro experiment of a certain drug mean that it is effective against a certain virus? In vitro experiments are effective, how far is it from becoming a reliable drug?
In this regard, in vitro experiments and studies have shown that it is effective. This is just a step in the process of developing new drugs or in the new use of old drugs. It does not mean that it can have the same effect in the human body. He explained: “The more important thing is to figure out its mechanism and whether the concentration of drugs that can inhibit the virus can be achieved in the human body. Taking ivermectin as an example, it is difficult to achieve in vitro experiments in humans. The concentration required to inhibit the virus is very large, which may far exceed the normal concentration for the treatment of parasitic diseases. If this concentration is followed, it may be very harmful to the human body, which is unrealistic.”
This is like using acids and alkalis to kill viruses, but humans cannot cure diseases by taking them.
The World Health Organization stated in a message on its official website: Except for clinical trials, it is not recommended to use ivermectin for COVID-19 pneumonia.
The U.S. Food and Drug Administration has also warned against using “unconventional treatments” for COVID-19 pneumonia, including ivermectin, that have not been approved or authorized by the agency.
Although Ivermectin is an “old medicine” with guaranteed safety, it is not safe to take it in super-normal doses or when humans take animal medicines. At present, the adverse effects of ivermectin in humans that have been monitored include dizziness, nausea, and diarrhea.
The World Health Organization stated that we must remain vigilant, not only to prevent COVID-19 pneumonia, but also to prevent future threats. In this regard, Unreliable and low-quality research may mislead doctors and may prevent some patients from receiving truly effective treatment.
(source:internet, reference only)
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