June 25, 2024

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The ketogenic diet may increase heart disease and cancer risk

The ketogenic diet may increase heart disease and cancer risk


The ketogenic diet may increase heart disease and cancer risk.

The ketogenic diet, or a disease-promoting diet, increases heart disease, cancer risk

Cardiovascular disease (CVD) is the leading cause of death in the world, and it is also the leading cause of death in many countries.

According to the statistics of the World Health Organization, nearly 18 million people die from cardiovascular diseases every year, accounting for more than 30% of the total number of deaths in the world. Cardiovascular disease mortality and morbidity remain high, and it is a major global public health problem that needs to be solved urgently.

The ketogenic diet (Keto Diet) is a high-fat, low-carbohydrate, protein and other nutritional element diet plan with a suitable ratio.

It was originally a non-drug therapy with effective efficacy for the treatment of refractory epilepsy in children.

In recent years, the ketogenic diet has become popular on the Internet, especially sought after by people who lose weight, and once became the pinnacle of diet in the weight loss industry.


When a person adopts a ketogenic diet, due to the low intake of carbohydrates and few sources of blood sugar, the body is forced to enter a state of “simulated hunger”. A high-speed fat-burning state to achieve weight loss.


Early studies show that short-term implementation of the ketogenic diet can indeed effectively lose weight, and the weight loss effect is even better than that of the traditional low-fat diet.

However, the ketogenic diet is often accompanied by obvious side effects, including fatigue, gastrointestinal dysfunction, arrhythmia, constipation, diarrhea, headache, stunting, etc.


On March 5, 2023, researchers at St. Paul’s Hospital in Canada and the University of British Columbia presented a new study at the American College of Cardiology Annual Scientific Sessions and World Congress of Cardiology .


Research has found that a ketogenic diet can increase levels of “bad” cholesterol, which doubles the risk of cardiovascular disease, including cardiovascular events, heart attack and stroke .


The ketogenic diet may increase heart disease and cancer risk



Generally speaking, the ketogenic diet is to limit carbohydrates to 10% of total daily calories, limit protein to 20%-30%, and obtain 60%-80% of daily calories from fat.


In the study, researchers analyzed about 70,684 participants in the UK Biobank database, collected participants’ diet through questionnaires, and drew blood to check cholesterol levels.

The researchers defined a low-carbohydrate, high-fat diet (LCHF) as having less than 25% of total daily energy from carbohydrates and more than 45% of total daily energy from fat.

Compared with a strict ketogenic diet, its carbohydrate Higher in compounds and lower in fat.


Using defined dietary criteria, the researchers identified 305 eligible participants and matched 1,220 participants on a regular diet by age and sex, with an average age of 54 years.

The relationship between low-carbohydrate, high-fat diets and risk of cardiovascular disease was analyzed.


The study found that participants on the LCHF diet had significantly higher levels of low-density lipoprotein cholesterol and apolipoprotein B, a group of low-density lipoproteins and other atherogenic lipoprotein particles, compared with participants on the conventional diet On the protein component, early research suggests that elevated apolipoprotein B may be a better predictor of cardiovascular disease risk than elevated bad cholesterol.


During an average follow-up period of 12 years, 9.8 percent of participants on the LCHF diet experienced new cardiovascular disease, compared with 4.3 percent of those on the standard diet, doubling the risk for participants on the LCHF diet.


The study found that participants on the LCHF diet had a two-fold higher risk of cardiovascular disease, including heart attack, stroke and peripheral arterial disease, compared with those on the regular diet .


Additionally, among participants on the LCHF diet, those with the highest levels of bad cholesterol had the highest risk of cardiovascular events.


This was an observational study and could only show an association between LCHF diet and an increased risk of major cardiac events, not cause and effect, the researchers said.


Previously, the American Association of Responsible Physicians and New York University and other researchers published a research paper entitled “Ketogenic Diets and Chronic Disease: Weighing the Benefits Against the Risks” in the ” Frontiers in Nutrition ” journal.


The study, the most comprehensive assessment to date of a ketogenic diet, suggests that it may cause long-term health damage after weighing the benefits and risks of the dietary strategy against chronic disease.


Studies have shown that a ketogenic diet increases the risk of several diseases, including heart disease, cancer, diabetes, and Alzheimer’s disease, outweighing its possible benefits .


The ketogenic diet may increases heart disease and cancer risk


In short, a healthy diet is the kingly way. No matter what kind of diet, only a reasonable combination can be beneficial to health, and if it is not chosen properly, it will be harmful.

Most diseases are related to diet to a large extent. Adjusting eating patterns and improving dietary structure are the shortcuts to prevent diseases.




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The ketogenic diet may increase heart disease and cancer risk

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