Vitamin A D deficiency in childhood may cause chronic diseases in adulthood!
- Stem Cell Therapy for Inflammatory Bowel Disease
- How about the safety and efficacy of novel CAR-T therapies?
- Even mild infection with COVID-19 can trigger long-lasting neuroinflammation
- Amyotrophic Lateral Sclerosis (ALS): Two new drugs failed in clinical trials!
- The “magic drug” metformin may make people live to 120 years old!
- Why do most smokers not get lung cancer?
Vitamin A D deficiency in childhood may cause chronic diseases in adulthood!
Vitamin A D deficiency in childhood may cause chronic diseases in adulthood! Sufficient vitamin A and D not only play a positive role in the prevention and treatment of early childhood diseases, but also related to the health of children in adulthood and prevent the occurrence of many chronic diseases, such as: cardiovascular diseases, tumors, metabolic disorders…
What is the overall nutritional status?
The overall nutritional level of children’s vitamin A and D is not up to standard, which is not optimistic.
The judgment index of vitamin A deficiency is serum retinol, and the judgment standard concentration: ≥1.05μmol/L (≥0.3 mg/L) is normal.
There are obvious regional differences and age differences in vitamin A deficiency. The younger the age, the higher the deficiency rate, which is higher in rural areas than in urban areas. More children are marginal vitamin A deficiency. Together, the overall vitamin A deficiency rate of children aged 3-5 in some countries is 29.3%, which is as high as 36.8% in rural areas. Almost one out of three children this age has insufficient vitamin A intake. The survey also found that the proportion of taking vitamin A supplements in urban areas is about 50%, while that in rural areas is less than 20%.
According to expert analysis, although this situation has certain economic factors, the main reason is the lack of supplementary awareness and the difference between urban and rural areas.
The indicator of vitamin D deficiency is serum 25(OH)D, and the concentration is ≥50nmol/L (20ng/mL) as normal.
The incidence of vitamin D deficiency and insufficiency among children aged 3-5 in some countries is about 51.9%, which is slightly higher in cities than in rural areas. In this way, half of 3-5 year old children are not vitamin D enough.
Believe it or not these numbers, but the pediatric doctors can’t calm down!
Do you know the reasons for vitamin A and D deficiency?
1 Insufficient storage during perinatal period
When maternal vitamin A and D levels are insufficient during pregnancy, what should be delivered to the fetus? Not to mention those weak premature babies, twin fetuses, low birth weight babies, etc., are more prone to vitamin A and D deficiency.
2 rapid growth and development
Infants and young children grow and develop faster, and they have relatively large requirements for vitamins A and D. They are generally the fastest within 6 months after birth, with an average length of 0.7 kg per month, whether they are catching up with growing premature babies or being tall and fat Of obese children, they are more prone to vitamin A and D deficiency.
3 insufficient nutrition
Even if the mother’s nutrition is very good, the vitamin A and D content in breast milk still cannot meet the growing needs of the baby’s physique; the vitamin D content in natural foods is less and the synthesis of vitamin D in the skin under ultraviolet light will be affected by many factors. The absorption and conversion rate of carotenoids is low. Exclusive breastfeeding and insufficient intake of complementary foods are more likely to lead to vitamin A and D deficiency.
4 the impact of the disease
Infectious diseases can cause a large loss of vitamin A and D in the body, and also affect the absorption and utilization of nutrients.
5 drug interference
Long-term use of cholestyramine, neomycin, anticonvulsants, antiepileptic drugs and glucocorticoids will affect the absorption and metabolism of vitamin A and D in the body.
Borderline vitamin A deficiency, vitamin D deficiency. Does it affect children’s health?
Yes, vitamin A and D deficiency is a gradual process. Long-term nutrient intake will cause the consumption of vitamin A and D stored in the body, and then the level of vitamin A and D in blood circulation will decrease, which will eventually lead to vitamin A and D. The lack of occurrence.
Experts believe that borderline vitamin A deficiency will also have adverse effects on growth and development, immune function and hematopoietic system. The clinical manifestations are increased prevalence and death risks for children in groups such as slow growth, repeated infections, and anemia. Insufficiency of vitamin D in childhood can lead to decreased bone mass and peak bone mass in adolescence, and significantly increase the risk of osteoporosis in adults. It also increases the risk of respiratory and digestive tract infections, as well as the risk of allergies and asthma.
It is worth noting that these adverse effects do not appear at the stage of vitamin A and D deficiency, but start to affect the body when the levels of vitamin A and D are lower than normal. Therefore, for vitamin A and D deficiency, the concept of prevention is more important. You cannot wait until the nutrient deficiency has already occurred to correct it.
How to reasonably interfere with babies
Vitamin AD nutrition?
The focus is on prevention. According to the consensus, the soldiers are divided into two ways: in order to prevent vitamin A and D deficiency, most babies should be supplemented with vitamin A 1500-2000IU/d and vitamin D 400-800IU/d after birth, and continue to supplement until 3 years old.
In addition, for those special populations, such individualized vitamin A and D supplementation can benefit children more.
- Premature babies, low birth weight babies, multiple births, etc. should be supplemented with vitamin A 1500-2000IU and vitamin D 400-800IU every day after birth. The upper limit should be supplemented for the first 3 months, and the lower limit can be adjusted after 3 months. In this way, for the first 3 months, take 1 red vitamin AD capsule a day for the next 3 months. Take 1 green vitamin AD capsule daily.
- Children with iron deficiency anemia and iron deficiency should be supplemented with vitamin A 1500-2000 IU and vitamin D 400-800 IU daily to promote the absorption and utilization of iron and improve the therapeutic effect of iron deficiency anemia.
- Children suffering from infectious diseases such as recurrent respiratory tract infections and diarrhea should be supplemented with 2000 IU of vitamin A and 400-800 IU of vitamin D every day to promote the recovery of children’s infectious diseases, improve the body’s immunity, and reduce the risk of infection.
- Children who also suffer from chronic diseases such as malnutrition, autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), etc. are also at risk of vitamin A deficiency and the severity of the disease is positively correlated with the degree of vitamin A deficiency. It is recommended to supplement 1500-2000 IU of vitamin A and 400-800 IU of vitamin D every day to help improve the nutritional status of sick children and improve the prognosis of chronic diseases.
The benefits of vitamin A and D
With the development of vitamin A intervention strategies, the typical vitamin A deficiency is much less, but the problem of borderline vitamin A deficiency still exists, and the vitamin A supplement program is still a suitable intervention method with significant cost-effectiveness. The prevention and treatment of vitamin D deficiency is still a prominent public health problem and an important task for pediatric health care workers.
Medical research has found that vitamins A and D have a synergistic effect on immune function, bone development, and prevention of anemia. Preventive supplementation measures will not cause vitamin A and vitamin D poisoning.
As two important fat-soluble vitamins, vitamin A and vitamin D nutrition affect the nutritional health and disease prevention of children from birth to the entire life cycle. hurry up!