- Merck diabetes drug Sitagliptin was hit by carcinogenic impurities
- CDC relaxes and reiterates its COVID-19 guidance
- How does NOVAVAX solve the dilemma when COVID-19 vaccine sales plummeted by 90%?
- Scientists develop new antibiotic molecule that kills several superbugs
- UK: The polio vaccine booster recommended for all children aged 1 to 9 in London
- Russia has discovered a new COVID-19 “Deltacron” hybrid variant
Can patients with gout and rheumatism receive COVID-19 vaccine?
Can patients with gout and rheumatism receive COVID-19 vaccine? Under the premise of stable disease, whether it is an inactivated vaccine has become a decisive factor for everyone’s vaccination.
The new coronavirus has raged wildly throughout 2020, and it is unbearable to look back. With the successful development of vaccines, it seems that there is hope of ending this great plague.
As various countries begin to vaccinate the COVID-19 vaccine, a question that the majority of rheumatic patients is very concerned about is: Can I get the COVID-19 vaccine?
General principles of vaccination for patients with rheumatism
For the special population of rheumatic immune diseases, including: systemic lupus erythematosus, rheumatoid arthritis, ankylosing spondylitis, Sjogren’s syndrome, etc., the European Union of Rheumatology has already given vaccination recommendations in 2019.
The general principle:
Vaccination can be given when the disease is stable; patients who are being treated with systemic glucocorticoids and immunosuppressive agents can be given inactivated vaccines; carefully consider the use of live attenuated vaccines; the timing of vaccination is best before immunosuppressive therapy, especially B cells Before removal treatment (eg, use of rituximab). Simply put, the key to vaccinating patients with rheumatism is: stable disease and inactivated vaccines. Under the premise of stable disease, whether it is an inactivated vaccine has become a decisive factor for everyone’s vaccination.
Is the COVID-19 vaccine an inactivated vaccine?
Inactivated vaccine, as the name implies, this vaccine has lost pathogen activity and will not cause disease to humans. It is produced by cultivating a complete whole virus in vitro for multiple generations, and then picking out the most unreplicated rookie virus, and injecting it into the human body to stimulate the body to produce a corresponding immune response. The neutralizing antibody is The most important part is also an indicator that we often use to evaluate vaccine potency.
Inactivated vaccines are traditional vaccine preparation methods and have been used clinically for a long time. The familiar measles vaccines, polio vaccines, and DPT vaccines are examples of inactivated vaccines. All of three new coronavirus vaccines currently developed in China are classified in this category. In principle, the majority of patients with rheumatism can be vaccinated normally as long as their condition is stable.
It is recommended to postpone the COVID-19 vaccine in the following situations
● Are younger than 18 years old or older than 59 years old;
● Those who are allergic to any ingredient in the vaccine, and those who have had severe allergic reactions to the vaccine in the past, such as acute allergic reactions, urticaria, skin eczema, dyspnea, angioedema or abdominal pain;
● Fever, acute disease, severe chronic disease, and those in the acute stage of chronic disease;
● Pregnant women and lactating women, have a family plan within 3 months of vaccination;
● Those with a history or family history of convulsions, epilepsy, encephalopathy, or mental illness; those with uncontrolled epilepsy and other progressive neurological diseases, and those with a history of Guillain-Barré syndrome;
● Has been diagnosed with congenital or acquired immunodeficiency, HIV infection, lymphoma, leukemia or other autoimmune diseases;
● Known or suspected of suffering from severe respiratory disease, severe cardiovascular disease, liver and kidney disease, malignant tumor;
● Those who use immunomodulators such as anti-tumor drugs;
● Those with a history of new coronavirus infection;
● Those who are considered unsuitable for vaccination by clinicians or vaccination staff.
●Other inactivated vaccines should be vaccinated within 14 days. Those who vaccinated other live attenuated vaccines within 28 days are advised to postpone vaccination; for those who have any discomfort before vaccination, postpone vaccination.
In general, as an inactivated vaccine, patients with rheumatism are not an absolute contraindication to the nCOVID-19 vaccination. However, no vaccine can guarantee 100% protection, and there is a certain percentage of risks in everything.
Experts believe that if you are in a high-risk area, you can get the COVID-19 vaccination if you have the conditions; if you are in a low-risk area, the vaccination unit is unwilling to vaccinate you, and we do not need to force it.
When the population vaccination rate expands and the number of new coronavirus pneumonia cases decreases, the risk of the majority of rheumatism patients being infected with COVID-19 is relatively low. It is also important to wear a mask, wash your hands frequently, pay attention to social distancing, go to places with less crowded air, and take good personal protection.
(source:internet, reference only)