May 28, 2024

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Diabetcis: Glycated Hemoglobin is a very important blood glucose indicator

Diabetcis: Glycated Hemoglobin is a very important blood glucose indicator

Diabetcis: Glycated Hemoglobin is a very important blood glucose indicator.  This article will give you a thorough understanding of Glycated Hemoglobin. Glycated Hemoglobin is a very important blood glucose indicator that diabetic patients often monitor.

Diabetcis: Glycated Hemoglobin is a very important blood glucose indicator

Why can glycosylated hemoglobin reflect blood sugar levels well? Why does the measurement of glycosylated hemoglobin reflect the average blood glucose level of the past 2 to 3 months, and doctors often recommend that patients regularly monitor the level of glycosylated hemoglobin to assess the status of blood glucose control? With all kinds of questions, I will reveal glycosylated hemoglobin for you The veil of mystery.


1. What is glycosylated hemoglobin?

Glycated hemoglobin is the product of the combination of hemoglobin in red blood cells and blood sugar. The higher the glycosylated hemoglobin, the more binding of blood sugar and hemoglobin, and the more serious the diabetes condition.


2. Why does it reflect the blood sugar level in the past two or three months?

We know that the life span of hemoglobin is about 2 to 3 months. By measuring the level of glycosylated hemoglobin, it can basically reflect the patient’s blood glucose level in the past 2 to 3 months.


3. Why do we need to test the blood glucose level 2 to 3 months ago?

Diabetics usually measure fasting blood glucose or postprandial blood glucose to monitor the diabetes condition and guide treatment. However, for type 1 diabetes patients with large blood glucose fluctuations and type 2 diabetes patients who are injected with insulin, only measure the instantaneous blood glucose 1 to 2 times, which cannot explain the longer The overall picture of the condition for a period of time has brought certain difficulties to the reasonable formulation of treatment plans. The measurement of glycosylated hemoglobin makes up for this deficiency, so it is known as the “gold standard” for diabetes monitoring.


4. What is the effect of increased glycosylated hemoglobin on the human body?

1) Change the affinity of red blood cells to oxygen, make tissues and cells hypoxia, and accelerate the formation of cardiovascular and cerebrovascular complications.

2) If the crystals in the eyes are glycated, it can cause cataracts.

3) Glycated hemoglobin can cause the glomerular basement membrane to thicken and induce diabetic nephropathy.

4) Glycated hemoglobin can also cause increased blood lipids and blood viscosity, which is an important factor in the occurrence of cardiovascular and cerebrovascular diseases. 


5. the reference value of glycosylated hemoglobin

The normal value of glycosylated hemoglobin is 4.4% to 6.2%, and it is required to be controlled below 11.5%. If it is greater than 12.6%, chronic complications are prone to occur. Generally speaking, for diabetic patients, it is better to control glycosylated hemoglobin below 7%. Of course, different people have different requirements for the control of glycosylated hemoglobin. Generally, it is required to be controlled below 7%; if the disease is relatively mild and younger, and there are no complications, it will be better to control it below 6.5%; but If patients are older, have a longer illness, and have many serious complications, especially those with cardiovascular disease, the control target for glycosylated hemoglobin will be relaxed accordingly, even more than 7.5%, and there are some more serious patients. Relax to 8%.


6. glycosylated hemoglobin cannot diagnose diabetes

Glycated hemoglobin is mainly used to evaluate the effect of blood sugar control and is not used for the diagnosis of diabetes. Normal glycated hemoglobin can only prove that the body’s blood glucose level is well regulated, and diabetes cannot be ruled out.

In addition, the identification of glycosylated hemoglobin for coma patients, the alertness of ketoacidosis, and the monitoring of gestational diabetes have clinical significance that cannot be ignored. Therefore, checking glycosylated hemoglobin has become an important indicator for understanding whether diabetes is well controlled. Foreign countries have used glycosylated hemoglobin monitoring as a “golden index” to determine the efficacy of diabetes and adjust the treatment plan.





(source:internet, reference only)

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