- Nature: Gastrointestinal virus can be transmitted through saliva
- First time: tRNA modifications in mitochondria shown to promote cancer metastasis
- The world first case: Humans were infected with the new coronavirus from cats
- New drug Zanubrutinib reduces tumor size in 80% of lymphoma patients
- Study shows robotic surgery is safer and reduces patient recovery time by 20%
- What is the relationship between Harmful metabolites of TME and antitumor immunity?
Blood sugar fluctuations case gastrointestinal suffering
Blood sugar fluctuations case gastrointestinal suffering. There are many reasons for abnormal gastrointestinal function in diabetic patients, such as poor long-term blood sugar control, abnormal lipid metabolism, high blood pressure, blood sugar fluctuations, obesity, smoking, etc.
If the long-term abnormal blood glucose affects the gastrointestinal function of the diabetic, it will have a major impact on the quality of life. The scientific name for diabetic patients with gastrointestinal pathology is “diabetic gastrointestinal autonomic neuropathy”, which is the most common chronic autonomic neuropathy of diabetes, with 4 specific manifestations.
1. Esophageal syndrome.
It is often manifested as early fullness, increased incidence of gastroesophageal reflux, and non-specific nausea.
Mainly manifested as postprandial fullness, upper abdominal distension, early satiety, nausea, vomiting, belching and other discomforts related to the slowing down of food emptying in the stomach.
3. Alternate diarrhea and constipation.
Mainly related to diabetes affecting intestinal movement. In some diabetic patients with a medical history of more than 10 years, in addition to alternating diarrhea and constipation, they often have severe diabetic peripheral neuropathy, including numbness, pain, and paresthesias in the hands and feet.
4. Peptic ulcer.
The proportion of diabetic patients with this disease is significantly higher than that of ordinary people. This is related to gastrointestinal dysfunction and abnormal gastric acid secretion in diabetic patients. Patients often present with heartburn, fasting pain or night abdominal pain, which is not easy to relieve.
There are many reasons for abnormal gastrointestinal function in diabetic patients, such as poor long-term blood sugar control, abnormal lipid metabolism, high blood pressure, blood sugar fluctuations, obesity, smoking, etc. Therefore, the following points need to be paid attention to in treatment: control blood sugar, in addition to achieving glycated hemoglobin standards, it is also necessary to reduce blood sugar fluctuations; lifestyle interventions include balanced nutrition, dietary rules, weight control, smoking cessation and alcohol restriction, and good bowel habits .
At the same time, patients can receive some treatments for pathogenesis, including anti-oxidative stress, nutritional nerve therapy, etc. Specific drugs include methylcobalamin and lipoic acid. For specific symptoms of the gastrointestinal tract, symptomatic treatment can be used, such as enhancing gastrointestinal motility, protecting gastric mucosa, and inhibiting gastric acid. Some patients have experienced permanent functional impairment, and treatment is mainly to improve the quality of life.
The key to diabetic gastrointestinal lesions lies in early recognition and timely treatment. The clinical diagnosis can be made through imaging and gastrointestinal endoscopy to exclude gastrointestinal malignant lesions, combined with gastric emptying test, Helicobacter pylori examination, and neuroelectromyography. diagnosis.
(source:internet, reference only)