April 15, 2024

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Pathogenic factors of gastrointestinal tumors

Pathogenic factors of gastrointestinal tumors


Pathogenic factors of gastrointestinal tumors.  Although the cause of cancer is not yet fully understood, experts generally believe that about 35-50% of malignant tumors are closely related to dietary and nutritional factors.

Pathogenic factors of gastrointestinal tumors

The digestive tract, as an organ that directly receives and digests food, will inevitably bear the brunt of the damage, and it is the hardest hit area.

It can be seen that good eating habits are essential!


What kind of eating habits lead to the occurrence of gastrointestinal tumors?

1. Gastric cancer

Stomach cancer is a common gastrointestinal tumor. At present, about 1 million people worldwide suffer from the disease every year, and some countries accounts for half of it. Approximately one person dies every minute. Among all cancers, stomach cancer is most closely related to eating.

Infection with Helicobacter pylori: The infection rate in some countries is 56%, and about 1% of infected people will develop gastric cancer. Helicobacter pylori is an important factor leading to gastric cancer;
Our country’s unique eating habits are the main reason for the high infection rate. Split meals and good hygiene are effective ways to prevent the spread of Helicobacter pylori.

Pickled, smoked, high-salt foods:

Pickled vegetables, bacon and other preserved foods contain a large amount of nitrite and secondary amines, which can synthesize nitrosamine compounds under the action of suitable acidity in the stomach or bacteria, and have strong carcinogenicity.

Processed foods:

such as dried meat, biscuits, preserves, etc., often also contain a lot of nitrite, so it is not advisable to eat too much.

Overnight leftovers:

Many people often eat leftovers to avoid waste. However, even if leftovers are reheated, they will increase the risk of stomach cancer.

Moldy and spoiled food:

Moldy is caused by contaminated molds. Some of the molds are toxin-producing fungi, which are very strong carcinogens. At the same time, certain foods produce large amounts of nitrite and secondary amines under the action of toxin-producing fungi. After entering the body, under certain conditions, the stomach can synthesize nitrosamine compounds and cause cancer.

Tobacco and alcohol stimulation:

It will stimulate the gastric mucosa to change, produce erosions, ulcers, polyps, gland atrophy, dysplasia, etc. and then become cancerous.

2. Colorectal cancer

Colorectal cancer is a common malignant tumor. In recent years, the global incidence rate has risen rapidly, with more than 1 million people getting sick every year. In some countries, the incidence rate can be said to be increasing rapidly, and the rate of increase far exceeds the international level.

Eating too well and moving too little

The “three high and one low” diet structure: namely: high fat, high protein, high calorie, low fiber.

The survey found that the faster the economic development, the higher the incidence of colorectal cancer. The reason is that people’s living standards have improved, eating too well and moving too little. High-fat, high-protein, low-fiber diet, and lack of exercise are all risk factors that increase the incidence of colorectal cancer.

Excessive consumption of pickled foods can lead to the occurrence of colorectal cancer.

A large amount of tobacco and alcohol, long-term failure to eat on time, staying up late, stress, etc., will cause disorders of the gastrointestinal function, and then induce colorectal cancer.

It is very important that many people are unwilling to do digital anal examination and colonoscopy, but they do not know that the early detection and cure rate is more than 90%. And 80% of colorectal cancers occur in the rectum.

To maintain healthy eating habits in life, you should eat more foods rich in carbohydrates and crude fiber, such as yam, corn, fruits, and fresh vegetables. These foods stay in the intestines for a short time and are beneficial to the elimination of intestinal toxins.

Try to eat less high-fat, high-protein foods, and avoid fruits, vegetables and foods that may spoil. At the same time maintain a healthy lifestyle, appropriately increase the amount of exercise, regular life rhythm, quit smoking and alcohol, and control weight.


3.  Liver cancer

Viral infection

People infected with hepatitis B virus, a considerable part of them, will eventually become chronic hepatitis, liver cirrhosis, and eventually lead to cancer. Many hepatitis B patients have insufficient knowledge and management of the disease, not only do not insist on taking antiviral drugs, but also do not take regular physical examinations, so that they develop liver cirrhosis and liver cancer, and they are too late to regret.


No matter how much alcohol you drink, what kind of alcohol is harmful to the human body. Alcohol damages the liver greatly, and liver function has a certain load. If the amount of alcohol consumed exceeds the load that the liver can bear, the load on the liver will increase and cirrhosis will occur. And if hepatitis B patients drink alcohol again, it will have a superimposed effect, and the damage to the liver can be imagined. Therefore, patients with hepatitis B and other viral hepatitis must avoid drinking alcohol, especially in the morning. This is because the liver is in a relatively exhausted state after digestion, metabolism and absorption overnight. Drinking at this time hurts the liver the most.

Fatty liver

Many recent studies have suggested that non-alcoholic fatty liver can also become cancerous. Therefore, if you do not pay attention to a healthy lifestyle, you develop fatty liver, and then develop into non-alcoholic fatty liver, it is possible to transform into liver cancer. Fatty liver is usually caused by an unhealthy lifestyle. Therefore, these people should improve their living habits by drinking less alcohol, consuming less lipids, and increasing exercise. Most fatty livers are reversible.

Moldy food

The carcinogenicity of aflatoxins in fungi is 75 times stronger than that of nitroamines, and the shortest time required for carcinogenesis is 24 weeks. All moldy food must be thrown away, and no human, livestock, or poultry can be eaten.

Animal and vegetable oils stored for too long

Stale oils all contain the chemical component of malondialdehyde, which can generate polymers and react with proteins and DNA in the human body, causing the structure of the protein to mutate, causing the cells with the mutated protein to lose their normal function and to start cancer. Cell transformation. In addition, the malondialdehyde polymer can hinder the replication of DNA and accelerate the aging process.

Although we are a big country with liver cancer, the rate of early diagnosis does not exceed 20%. In our neighboring country, Japan, the early rate of liver cancer can account for more than 50% of all liver cancers. We hope that through our continuous efforts, health education will be strengthened, so that more patients can understand their own conditions and pay attention to their lifestyles, so as to prevent the occurrence of liver cancer.

4. Esophageal cancer

The main factor of esophageal cancer is related to diet.

Nitrosamines and molds:

Nitrosamines are closely related to esophageal cancer, and mold can enhance the carcinogenic effects of nitrosamines. It is necessary to fast overnight vegetables, rotten fruits, moldy grains, commercially available salted fish and bacon and pickles, as well as fried, fried, and grilled foods. Pay attention to the source of drinking water, and prevent the tap water from being polluted.

Tobacco and alcohol:

Smoking has a wide range of carcinogens, and the formation of cancer can cause cancers of the digestive, respiratory, and urinary tracts. Long-term heavy drinking will inevitably not eat carcinogens. Some wine contains carcinogens such as nitrosamines and aflatoxin, as well as indirect carcinogens such as aldol.


Malnutrition is related to esophageal cancer. Protein deficiency can cause esophageal mucosal hyperplasia, which is prone to malignant transformation; fat deficiency hinders the absorption of essential fatty acids and fat-soluble vitamins, affects health and reduces immune function. Eat more fresh vegetables and fruits, the former cannot replace the latter, because a lot of vitamins and trace elements are often destroyed in cooking.

To promote tea drinking. Green tea can prevent cancer and is beneficial to cardiovascular diseases. But it is not advisable to drink booze, it is best to taste it, and drink a small amount effectively in the body many times. When pregnant, breastfeeding, fever, bleeding and gastrointestinal disease, do not drink carefully.

Deficiency of trace elements:

Patients suffering from esophageal cancer often lack iron, molybdenum, zinc, manganese, selenium and other trace elements and vitamins A, B2, and C; aspirin can prevent this disease, so high-risk groups can supplement related trace elements and vitamins under the guidance of a physician And drugs to prevent.

Rough eating, overheating, and gorging:

Foods above 65°C are listed as carcinogens by the WHO; too hot, too rough, and eating too fast will prevent the food from being adequately chewed. Rough, high-temperature meals can easily damage the fragile esophageal mucosa. The epithelium ruptures, deforms over time and causes cancer.


5. pancreatic cancer

Genetic factors account for only 5%, and environmental factors account for 95%. Among them, diet and obesity (30-35%) accounted for the largest proportion. In addition, smoking and inflammation are also some important triggers.


The risk of pancreatic cancer in long-term heavy smokers is 2 to 2.5 times that of non-smokers, and the age of onset will be 10 to 15 years earlier.

Alcoholism and binge eating:

This will cause long-term irritation of the pancreas, leading to chronic inflammation of the pancreas and inducing cancer.

High-sugar, high-fat, high-protein diet:

Long-term excessive intake of sweets, sugary drinks, meat and other foods will stimulate the gastrointestinal tract to release some hormones, increase the sensitivity of the pancreas to carcinogens, and significantly increase the risk of pancreatic cancer.

Too much coffee:

Long-term consumption of large amounts of coffee can increase the risk of pancreatic cancer by 3 to 4 times.

Fried food:

The amino acids and proteins in these foods will decompose carcinogens when they are fried at high temperature, and long-term intake is not conducive to pancreatic health.

Lack of exercise:

Sedentary and obesity are one of the main causes of pancreatic cancer; persistent exercise is beneficial to promote food digestion and absorption, and improve body metabolism.

Chemical factors:

Long-term exposure to toxic chemicals such as naphthylamine and aniline can increase the risk of pancreatic cancer by 5 times!

Chronic inflammation:

Diabetes and chronic pancreatitis may also induce cancer.


6. The blacklist of carcinogenic foods announced by the Chinese Academy of Medical Sciences

Pickled food:

Dimethyl nitrite produced by salted fish can be converted into carcinogen dimethyl nitrite in the body. Salted eggs, pickles, etc. also contain carcinogens and should be eaten as little as possible.  

Barbecued food:

Roast beef, roast duck, roast lamb, roast goose, roast suckling pig, roast lamb skewers, etc., should not be eaten more because of the strong carcinogens. 

Smoked food:

Such as bacon, smoked liver, smoked fish, smoked eggs, smoked dried tofu and other carcinogens containing benzopyrene, regular consumption is prone to esophageal cancer and gastric cancer.

Fried food:

After the food is fried, polycyclic aromatic hydrocarbons, which are carcinogens, will be produced.

Moldy food:

Rice, wheat, beans, corn, peanuts and other foods are susceptible to damp and mildew. When they are contaminated by molds, they will produce carcinogenic toxins—aflatoxins. 

Cook cabbage and sauerkraut overnight:

It produces nitrite, which is converted into carcinogenic nitrite in the body.  


Oral cancer, pharynx cancer, laryngeal cancer, esophageal cancer, liver cancer, postmenopausal breast cancer, and the carcinogenic effects of alcohol in the human body can be said to be full bloom.


7. The red list of anti-cancer foods announced by the Chinese Academy of Medical Sciences

  • tomato
  • green vegetables
  • Shallots, garlic, onions
  • Citrus fruits
  • Cruciferous vegetables (cabbage, radish, cabbage, rape, cauliflower, etc.)
  • Soybeans, grains
  • Wheat bran (wheat husk, whole wheat noodles)
  • Low-fat milk


(source:internet, reference only)

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