June 26, 2022

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The global burden of adolescent and young adult cancer in 2019

The global burden of adolescent and young adult cancer in 2019



 

The global burden of adolescent and young adult cancer in 2019.

Lancet Oncology: The global burden of cancer among young people is released, cancers kill 400,000 people every year.

 

In recent years, due to factors such as diet, environment, and population aging, the global cancer incidence has continued to increase, and cancer as the main cause of death has become increasingly prominent.

Compared with the elderly, young cancer patients are often ignored.

However, research data in recent years has shown that cancer is showing a younger trend, and the incidence of cancer in young people has shown an upward trend in recent years.

 

On December 3, 2021, the “Lancet Oncology” published an article titled: The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Research papers for Study 2019 .

 

The study showed that there were 1.19 million new cancers among adolescents and young people aged 15-39 , and 396,000 deaths from cancer.

The top five cancers with cancer burden are: leukemia, breast cancer, brain and central nervous system cancer, colorectal cancer and gastric cancer. Cancer has become the fourth leading cause of death among adolescents and young people worldwide.

 

The global burden of adolescent and young adult cancer in 2019

 

In the study, the researchers analyzed the results of the 2019 Global Burden of Disease, Injury, and Risk Factors Study (GBD) , with a focus on the results of disability-adjusted life years (DALY) to inform adolescents and young people of global cancer control measures .

The study used the age range of 15-39 years to define adolescents and young adults.

 

Overall, in 2019, there were 1.19 million new cancer cases and 396,000 deaths from cancer among adolescents and young adults.

The top five cancers are: leukemia, breast cancer, cancer and central nervous system cancer, colorectal cancer and gastric cancer.

Adolescents and young adults’ cancer contributes 23.5 million DALYs to the global burden of disease.

Cancer has become the fourth leading cause of death among adolescents and young people worldwide.

 

 


Top 5 Young People’s Cancer Burden

 

Breast cancer (10.6%), brain and central nervous system cancers (7.4%), colorectal cancer (7%)and gastric cancer (6.7%)are the top four cancers of the global burden of cancer among young people.

If leukemia is regarded as one Group, regardless of subtype, leukemia will become the largest cancer burden for young people, accounting for 12%.

 

The global burden of adolescent and young adult cancer in 2019

 

 


Cancer distribution area

 

Cancers in adolescents and young adults aged 15-39 are mainly concentrated in parts of Asia, sub-Saharan Africa and South America.

 

The global burden of adolescent and young adult cancer in 2019

 

 


Cancer distribution age

 

Among all age groups, individuals aged 35-39 account for the largest proportion of cancers aged 15-39. While the proportion of leukemia decreases with age, the overall proportion of cancer increases with age.

 

The global burden of adolescent and young adult cancer in 2019

 

Analysis of youth cancer data in 2019 by age

 

In addition, the proportion of other types of cancer is higher, the highest among 15-19 year olds, and the lowest among 35-39 year olds. When directly comparing the DALY burden ratio between 15-29 years old and 30-39 years old age group, it is found that the main cause has gradually changed from leukemia and lymphoma to other types of cancer, especially breast and cervical cancer.

 

 


Differences between men and women

 

For women, the top five causes of the cancer burden of women worldwide are breast cancer, cervical cancer, other cancers, stomach cancer, and brain and central nervous system cancers.

 

For men, the top five causes of the global burden of male cancer are: other cancers, cancers of the brain and central nervous system, colorectal cancer, tracheobronchial and lung cancer, and gastric cancer.

 

Analysis of 2019 Youth Cancer Data by Gender

 

Taken together, the overall incidence of cancer in women is higher than that in men, and the absolute mortality rate is similar.

Breast cancer and cervical cancer account for a large proportion of the global burden of cancer in women.

According to cancer data in 2019, the cancer burden of cancer among adolescents and young people aged 15-39 ranks tenth in the world, and cancer has become the fourth leading cause of death among adolescents and young people in the world.

 

 


Summary

 

In summary, the study reflects the global burden of cancer among adolescents and young people .

In terms of mortality and disability-adjusted life years (DALY) , the global cancer burden is huge among adolescents and young people.

These results provide new insights into the distribution and scale of the global burden of cancer among adolescents and young adults.

 

 

 

Paper link:

https://doi.org/10.1016/S1470-2045(21)00581-7

The global burden of adolescent and young adult cancer in 2019

(source:internet, reference only)


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