Foods with rich flavonoids make you live longer without dementia!
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Foods with rich flavonoids make you live longer without dementia!
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Neurology: Foods with rich flavonoids make you live longer without dementia!
Flavonoids are a group of biologically active phenolic compounds, a subset of phytonutrients found in abundance in different plant foods. Flavonoids are found in different types of fruits, vegetables, nuts, seeds, spices, grains, bark, roots, stems, flowers and other plant foods as well as in beverages such as tea and wine.
A new study previously published in the international academic journal Nature Communications shows that eating foods rich in flavonoids, such as apples and tea, can protect against cancer and heart disease, especially in smokers and alcoholics.
With the increasing use of flavonoids through a diet rich in fruits and vegetables, different studies have been conducted around the world to evaluate their potential health benefits and anticancer properties.
In order to prospectively study the relationship between long-term dietary flavonoids and subjective cognitive decline (SCD), experts from Harvard University and Zhejiang University conducted a related study, the results were published in the journal Neurology.
Researchers followed 49,493 women in the Nurses’ Health Study (NHS) (1984-2006) and 27,842 men in the Health Professionals Follow-up Study (HPFS) (1986-2002). Poisson regression was used to assess the association between dietary flavonoids (flavonols, flavonoids, flavanones, flavan-3-ols, anthocyanins, polymeric flavonoids, and procyanidins) and subsequent SCD.
Higher total flavonoid intake was associated with lower odds of SCD after adjusting for age, total energy intake, major nondietary factors, and specific dietary factors. A 3-unit increment of SCD had a pooled risk reduction of 19% in the highest versus lowest quintile of total flavonoid intake (OR=0.81, 95% CI: 0.76, 0.89).
Further in the pooled results, flavonoids (OR=0.62 [95% CI 0.57, 0.68]), flavanones (OR=0.64 [0.58, 0.68]) and anthocyanins (OR=0.76 [0.72, 0.84] were observed ) had the strongest association, reducing the risk by 38%, 36%, and 24%, respectively. The dose-response curve was the steepest for flavonoids, followed by anthocyanins. Finally, the article also noted that many foods rich in flavonoids, such as strawberries, oranges, grapefruit, citrus juice, apples/pears, celery, peppers, and bananas, were significantly associated with a lower risk of SCD.
The relationship between intake of different flavonoids and SCD
Taken together, the results support a benefit of higher flavonoid intake for maintaining cognitive function in U.S. men and women.
references:
Long-term Dietary Flavonoid Intake and Subjective Cognitive Decline in US Men and Women. Neurology Sep 2021, 97 (10) e1041-e1056; DOI: 10.1212/WNL.0000000000012454
Neurology: Foods with rich flavonoids make you live longer without dementia!
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