Obesity will increase 6 fatal risks like Depression Cancer Cardiovascular diseases….

Obesity will increase 6 fatal risks like Depression Cancer Cardiovascular diseases…… 10 recent studies have shown that obesity can increase the risks of Alzheimer’s disease, depression, cancer, cardiovascular disease, death from COVID-19 pneumonia, and shortened life expectancy.

High risk of Alzheimer’s disease

Recently, in a research report published in the Journal of Alzheimer’s Disease Reports, researchers from the University of Sheffield in the United Kingdom and other institutions pointed out that being overweight may accelerate the development of Alzheimer’s disease. Occurrence and influence effects, obesity may lead to the susceptibility of nerve tissue; previous studies have suggested that Alzheimer’s disease is related to the damage of the brain by periodontitis pathogens. On the contrary, if patients with mild Alzheimer’s disease can maintain a healthy weight, it can help maintain the brain structure and delay the progression of Alzheimer’s disease.

In addition, in a research report published in the International Journal of Epidemiology, a study by University College London and other institutions found that compared with people with a normal body mass index (BMI), obese people are The risk of dementia is 31% higher. And compared with men, women are at higher risk. On the contrary, scientific weight management is the key to reducing the risk of dementia.

High risk of psychological problems such as depression

Researchers from Sweden’s Lund University and other institutions have recently discovered that half of young people who have received severe obesity treatment have neuropsychiatric problems. According to reports from themselves or their parents, two-thirds of teenagers have some type of mental health problem.

In recent years, the incidence of obesity and mental illness among young people has increased significantly. Researchers have previously observed a link between obesity and depression and eating disorders.

Cancer and its metastasis, high genetic risk

Recently, a large study involving more than 100,000 people conducted by the University of Bristol in the United Kingdom and the International Agency for Research on Cancer found that men with a higher body mass index (BMI) are at greater risk of cancer and have a higher waist-to-hip ratio (in addition to waist circumference). Women with hip circumference) are at greater risk of cancer. In addition, in a research report published in the journal Cell, a study from Harvard University School of Medicine and other institutions found that obesity and high-fat diet can reduce the number of cytotoxic T lymphocytes and anti-tumor activity. Deprive T lymphocytes of fuel and accelerate tumor growth.

In addition to accelerating tumor growth, obesity also increases cancer metastasis and genetic risk. A study conducted by institutions such as Tufts University in the United States revealed the association between obesity and cancer metastasis: The risk of cancer metastasis is particularly high in certain populations, including obese people.

In terms of genetic risk, in an animal study published in the Journal of Hepatology, researchers found a tiny ribonucleic acid in obese female mice, which seemed to transmit liver cancer susceptibility and increase Odds of liver cancer in offspring and offspring.

High risk of cardiovascular and metabolic diseases

A few days ago, in a research report published in PLoS Medicine, researchers from Loughborough University and other institutions in the United Kingdom found that the longer a person is obese, the more cardiovascular and metabolic diseases will occur. The greater the risk. The researchers said that not all obese people have the same cardiovascular and metabolic risk factors, but the length of time a person is obese in their lifetime may affect this difference.

High risk of death from COVID-19 pneumonia

Recently, a study published in the Annals of Internal Medicine by the Caesars Medical Institution in Southern California, USA, pointed out that there is a significant difference between the risk of death of patients with COVID-19 pneumonia and their body mass index (BMI). Associated. By analyzing the medical health records of more than 6,900 patients with COVID-19 pneumonia, the researchers found that within 21 days after being diagnosed with COVID-19 pneumonia, the mortality rate of patients with higher weight was four times that of patients with normal weight.

High risk of aging and shortened life expectancy

An article published in the “Obesity” magazine pointed out that obesity should be regarded as a disease of aging. Studies have shown that after the age of 40, obesity shortens the life expectancy of men by 5.8 years and the life expectancy of women by 7.1 years. Obese patients also have other signs of aging, including the “clock of life”-shortening of telomeres, systemic inflammation, and decline in organ function.

Specifically, obesity can damage the integrity of nuclear DNA and mitochondrial DNA, as well as change DNA methylation patterns, which are all related to the epigenetic aging of different tissues.

(source:internet, reference only)

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