BMJ: Summary of the efficacy of various COVID-19 vaccines

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BMJ: Summary of the efficacy of various COVID-19 vaccines

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BMJ: Summary of the efficacy of various COVID-19 vaccines

Recently, BMJ Medicine , a subsidiary of the British Medical Journal, published a review paper titled: Covid-19: virology, variants, and vaccines , outlining the virology, mutants, and vaccines of the new coronavirus.

Since the outbreak of the COVID-19 virus, the WHO has been paying attention to the mutation of the COVID-19 virus.

As of January this year, a total of 5 highly concerned variants (variants of concern) , 2 worthy of attention (variants of interest) , and 3 Variants are being tested.

The table below lists the names of these variants, the spike protein mutations, and when and where they were first discovered.

As of January 24, 2022, a total of 33 COVID-19 vaccines have been approved worldwide and used in 197 countries, of which 10 COVID-19 vaccines have been approved by the World Health Organization (WHO) for emergency use.

As of January 25, 2022, there are 194 vaccines in preclinical development and 140 in clinical development worldwide.

Numerous studies have explored the effectiveness of these approved vaccines, however, from the reported data, the effectiveness of these vaccines varies widely.

This difference may be due to several factors in the study, including the country, time and population size of the study, and the type of SARS-CoV-2 variant that spread during the study period.

These complex factors mean that it is difficult to directly compare the effects of these vaccines.

The table below lists public data on several COVID-19 vaccines that have received emergency approval from the WHO.

They are:

• Pfizer/BioNTech’s mRNA vaccine – BNT162b2,
• Oxford University/AstraZeneca’s adenovirus vector vaccine – ChAdOx1,
• Johnson & Johnson’s adenovirus vector vaccine – Ad26.COV2.S,
• Moderna’s mRNA vaccine – mRNA-1273 ,
• Sinopharm’s inactivated virus medicine – BBIBP-CorV,
• Sinovac’s inactivated virus vaccine – CoronaVac,
• India Bharat Bio’s whole virus inactivated vaccine – Covaxin,
• Novavax’s protein subunit vaccine – NVX -CoV2373.

Reference:
https://bmjmedicine.bmj.com/content/1/1/e000040

BMJ: Summary of the efficacy of various COVID-19 vaccines

(source:internet, reference only)

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